Perifollicular Doppler in Natural Cycle In Vitro Fertilization
This study is currently recruiting participants.
Verified August 2012 by OVO R & D
Sponsor:
OVO R & D
Information provided by (Responsible Party):
OVO R & D
ClinicalTrials.gov Identifier:
NCT01668212
First received: June 19, 2012
Last updated: August 23, 2012
Last verified: August 2012
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Purpose
Perifollicular Doppler could reflect the quality of the follicle's vascularization and, consequently, the one of the oocyte that ensues from it. Perifollicuar Doppler is the analysis, in ultrasound, of the blood flow in vessels surrounding the follicle.
The goal of this study is to evaluate if there is a link, in natural cycle In Vitro Fertilization, between the quality of the vascularization and the one of the oocyte, the embryo and the pregnancy.
| Condition | Intervention |
|---|---|
|
Infertility |
Procedure: Doppler ultrasound |
| Study Type: | Observational |
| Study Design: | Observational Model: Case-Only Time Perspective: Prospective |
| Official Title: | Perifollicular Doppler in Natural Cycle In Vitro Fertilization |
Resource links provided by NLM:
Further study details as provided by OVO R & D:
Primary Outcome Measures:
- Quality perifollicular doppler and quality of the oocyte [ Time Frame: 2 weeks ] [ Designated as safety issue: No ]The measurements are done twice; on days of induction and oocyte retrieval. During the blood sample collection on the day of the induction, there is also a measurement of progesterone, estradiol and luteinizing hormone (LH).
| Estimated Enrollment: | 94 |
| Study Start Date: | March 2012 |
| Groups/Cohorts | Assigned Interventions |
|---|---|
|
natural In Vitro Fertilization cycle
Patient doing following natural In Vitro fertilization cycle
|
Procedure: Doppler ultrasound
Doppler Ultrasound
|
Eligibility| Ages Eligible for Study: | 18 Years to 38 Years |
| Genders Eligible for Study: | Female |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Probability Sample |
Study Population
Women following In Vitro Fertilization cycle
Criteria
Inclusion Criteria:
- Patient with a natural In Vitro Fertilization cycle.
- Patient under 38 years old
- Body mass indice under 35
- Ovulatory cycles between 20-35 days
Exclusion Criteria:
- Patient with a stimulation In Vitro Fertilization cycle
- Patient with a naturalIn Vitro Fertilization cycle with egg donor
- Patient with a natural In Vitro Fertilization cycle with freezing embryo
- Smoking patient
- Diabetic patient
- Patient with treatment of antihypertensive drug, anticoagulant, antiplatelet, vasodilator
- Body mass indice over 35
- Patient over 38 years old
- Patient without ovulation or cycle over 35 days
- Percutaneous Epididymal Sperm Aspiration (PESA), Testicular Sperm Extraction (TESE) or micro TESE
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01668212
Contacts
| Contact: Cynthia Levesque | 514-798-2000 ext 755 | c.levesque@cliniqueovo.com |
| Contact: Michael Harnois | 514-798-2000 ext 755 | m.harnois@cliniqueovo.com |
Locations
| Canada, Quebec | |
| Ovo Fertilité | Recruiting |
| Montréal, Quebec, Canada, H4P 2S4 | |
| Contact: Shirley Brugerie, director (514) 798-2000 ext 753 s.brugerie@cliniqueovo.com | |
| Principal Investigator: Delphine Delrieu, MD | |
Sponsors and Collaborators
OVO R & D
Investigators
| Principal Investigator: | Delphine Delrieu, MD | Clinique ovo |
More Information
No publications provided
| Responsible Party: | OVO R & D |
| ClinicalTrials.gov Identifier: | NCT01668212 History of Changes |
| Other Study ID Numbers: | OVO-11-01 |
| Study First Received: | June 19, 2012 |
| Last Updated: | August 23, 2012 |
| Health Authority: | Canada: Ethics Review Committee |
Additional relevant MeSH terms:
|
Infertility Genital Diseases, Male Genital Diseases, Female |
ClinicalTrials.gov processed this record on May 19, 2013