Durability of Virologic Response and/or Viral Resistance Patterns in Participants With Chronic Hepatitis C Who Have Been Previously Treated With MK-5172 (MK-5172-017 AM1)
This three-year multicenter study is being done to follow participants who received at least one dose of MK-5172 in a previous study to determine if they remain hepatitis C virus (HCV)-RNA negative over time, and to determine if they have developed antiviral resistance. The study will also evaluate long-term adverse events in this population.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||A Long-Term Follow-Up Study to Evaluate the Durability of Virologic Response and/or Viral Resistance Patterns of Subjects With Chronic Hepatitis C Who Have Been Previously Treated With MK-5172 in a Prior Clinical Trial|
- Time to Viral Relapse [ Time Frame: From Last Dose of MK-5172 Up to ~ 36 Months After Enrollment in This Study ] [ Designated as safety issue: No ]
- Number of Participants With Antiviral Resistance [ Time Frame: From Last Dose of MK-5172 Up to ~ 36 Months After Enrollment in This Study ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples With DNA
Blood samples will be collected and retained for purposes of DNA testing and plasma will be retained for future biomedical research.
|Study Start Date:||December 2012|
|Estimated Study Completion Date:||September 2018|
|Estimated Primary Completion Date:||September 2018 (Final data collection date for primary outcome measure)|
Participants previously received MK-5172 as study treatment.
MK-5172 was not administered to participants in the course of this study.
Other Name: Participants previously received study treatment with MK-5172 at the dose and frequency specified in the study protocol.