Evaluation of the Zilver® Vena™ Venous Stent (VIVO EU)

This study is currently recruiting participants.
Verified November 2012 by Cook
Sponsor:
Information provided by (Responsible Party):
Cook
ClinicalTrials.gov Identifier:
NCT01663051
First received: August 6, 2012
Last updated: November 28, 2012
Last verified: November 2012
  Purpose

This prospective, non-randomized, multi-center study is intended to evaluate the Zilver® Vena™ stent in the treatment of symptomatic iliofemoral venous outflow obstruction.


Condition Intervention
Iliofemoral Venous Outflow Obstruction
Device: Zilver Vena Venous Stent

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Evaluation of the Zilver® Vena™ Venous Stent

Further study details as provided by Cook:

Primary Outcome Measures:
  • Major Adverse Events [ Time Frame: 1 month ] [ Designated as safety issue: Yes ]
  • Patency [ Time Frame: 12 months ] [ Designated as safety issue: No ]
    Assessed via ultrasound


Estimated Enrollment: 35
Study Start Date: November 2012
Estimated Study Completion Date: June 2014
Estimated Primary Completion Date: June 2014 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Stent
Stent
Device: Zilver Vena Venous Stent
Stenting iliofemoral venous outflow obstruction

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Patients with symptomatic iliofemoral venous outflow obstruction.

Criteria

Inclusion Criteria:

  • Symptomatic venous outflow obstruction in up to two iliofemoral venous segments (one in each limb), demonstrated by:
  • CEAP 'C' ≥ 3, or
  • VCSS pain score ≥ 2

Exclusion Criteria:

  • < 18 years of age
  • Pregnant or planning to become pregnant in the next 12 months
  • Planned surgical or interventional procedures (except thrombolysis and thrombectomy in preparation for the procedure or vena cava filter placement prior to stent implantation in patients at high risk for pulmonary embolism) within 30 days prior to or after the study procedure.
  • Lesions with intended treatment lengths extending into the inferior vena cava or below the level of the lesser trochanter
  • Previous stenting of the target vessel
  • Iliofemoral venous segment unsuitable for treatment with available sizes of study devices
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01663051

Contacts
Contact: Ashley Hughes, MS 765-463-7537 ahughes@medinst.com
Contact: Lars Stage +45 56868686 lars.stage@cookmedical.com

Locations
Denmark
Gentofte Hospital Recruiting
Gentofte, Denmark, 2900
Contact: Niels Baekgaard, Assoc. Prof.     +45 3977 7508     nibae@geh.regionh.dk    
Ireland
Galway University Hospitals Recruiting
Galway, Ireland
Contact: Gerard O'Sullivan, Dr. Med     +35 3 915 423 56     Gerard.osullivan2@hse.ie    
Spain
Hospital Madrid Monteprincipe Recruiting
Madrid, Spain
Contact: Marta R. Ortega, Dr. Med     +34 61 92 07 922     pgusanian@gmail.com    
Sponsors and Collaborators
Cook
  More Information

No publications provided

Responsible Party: Cook
ClinicalTrials.gov Identifier: NCT01663051     History of Changes
Other Study ID Numbers: 10-018
Study First Received: August 6, 2012
Last Updated: November 28, 2012
Health Authority: Denmark: Ethics Committee
Spain: Ethics Committee
Italy: Ethics Committee
Ireland: Research Ethics Committee

ClinicalTrials.gov processed this record on May 16, 2013