Effects of Pleural Effusion Drainage on Respiratory System Mechanics
Recruitment status was Not yet recruiting
The effects of pleural drainage on lung mechanics are unknown. Insertion of esophageal balloon will allow us to measure and assess pleural pressure, and thus assess any possible effects of pleural fluid drainage may have on lung mechanics.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Effects of Pleural Effusion Drainage on Respiratory System Mechanics in Mechanically Ventilated Patients, as Measured by Esophageal Balloon.|
- chest wall and lung compliance [ Time Frame: 1 year ] [ Designated as safety issue: No ]The use of esophageal balloon allows us to partition respiratory system into its components, namely, chest wall and lung compliance. These measurements have not been described so far in patients undergoing pleural fluid drainage. Thus, assessment of esophageal pressure which is a surrogate of pleural pressure will allow us an accurate measurement of the effect of pleural fluid drainage on chest wall and lung mechanics.
- oxygenation [ Time Frame: 1 year ] [ Designated as safety issue: No ]We suspect that pleural fluid drainage will be associated with improved chest wall and lung mechanics. If this will be the case, then we expect a concomitant improvement in oxygenation.
|Study Start Date:||July 2012|
|Estimated Study Completion Date:||July 2013|
|Estimated Primary Completion Date:||July 2013 (Final data collection date for primary outcome measure)|
candidates for pleural fluid drainage
patients who are candidates for pleural fluid drainage.
Esophageal balloon will be inserted prior to pleural fluid drainage.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01652521
|Contact: Arie Soroksky, M.D.||email@example.com|
|Wolfson MC||Not yet recruiting|
|Principal Investigator: Arie Soroksky, MD|
|Principal Investigator:||Arie Soroksky, MD||Wolfson MC|