Difference in Grades of Epiblepharon According to Positional Changes and General Anesthesia
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Purpose
Epiblepharon is a very common condition among Asian children and is a fold of the skin and underlying pretarsal orbicularis muscle that overlaps the eyelid margin and pushes the lashes against the cornea. It is manifested by the anterior lamella overriding the posterior lamella which causes the lashes to brush against the cornea. Although the prevalence of epiblepharon is known to be high among Asians, its cause remains controversial. Several etiological factors may be involved in the pathogenesis of epiblepharon.
Although epiblepharon in the lower lids lessens and disappears with age in many cases, surgery must be performed at an early age in severe cases in order to prevent ocular trauma as the vertically oriented cilia of the lashes can erode the corneal epithelium. Induced keratitis and astigmatism are indications for surgical intervention.
Over our many years of surgical experience, the investigators came to realize that the severity of epiblepharon was reduced when patients were under general anesthesia during surgery. The purpose of this study was to investigate the role of the orbicularis muscle in the pathogenesis of lower lid epiblepharon and to analyze the differences in the severity of epiblepharon in the upright versus the supine position and before and after the induction of general anesthesia.
| Condition |
|---|
|
Epiblepharon |
| Study Type: | Observational |
| Study Design: | Observational Model: Case-Only Time Perspective: Retrospective |
- Degree of skin fold height [ Time Frame: 1 hour before epiblepharon surgery ] [ Designated as safety issue: No ]
| Estimated Enrollment: | 63 |
| Study Start Date: | July 2012 |
| Estimated Study Completion Date: | September 2012 |
| Primary Completion Date: | July 2012 (Final data collection date for primary outcome measure) |
| Groups/Cohorts |
|---|
|
Epiblepharon
subjects demonstrating prominent corneal touch by cilia and/or related subjective symptoms
|
Eligibility| Ages Eligible for Study: | 1 Year to 12 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Subjects with epiblepharon which needed surgical correction
Inclusion Criteria:
- subjects younger than 12 years
- more than 12 months' follow-up
- subjects demonstrating prominent corneal touch by cilia and/or related subjective symptoms
- subjects who underwent general anesthesia for surgical correction of epiblepharon
Exclusion Criteria:
- subjects older than 12 years
- less than 12 months' follow-up -. subjects who underwent surgery on local anesthesia
Contacts and Locations
More Information
No publications provided by Yonsei University
Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
| Responsible Party: | Yonsei University |
| ClinicalTrials.gov Identifier: | NCT01650688 History of Changes |
| Other Study ID Numbers: | 4-2012-0315 |
| Study First Received: | July 15, 2012 |
| Last Updated: | July 23, 2012 |
| Health Authority: | South Korea: Institutional Review Board |
Keywords provided by Yonsei University:
|
Epiblepharon, general anesthesia, positional change |
ClinicalTrials.gov processed this record on May 16, 2013