The Effect of Thyme and Sumac on the Thermic Effect of Food and Comparison Between Warm and Cold Temperament People

The recruitment status of this study is unknown because the information has not been verified recently.
Verified July 2012 by Tehran University of Medical Sciences.
Recruitment status was  Not yet recruiting
Sponsor:
Information provided by (Responsible Party):
Tehran University of Medical Sciences
ClinicalTrials.gov Identifier:
NCT01643096
First received: July 15, 2012
Last updated: July 16, 2012
Last verified: July 2012
  Purpose

The purpose of this study is to determine the effect of Zataria multiflora Boiss and Sumac on the thermic effect of food, activity of sympathetic - parasympathetic system: comparison between warm and cold temperament people.


Condition Intervention
Effects of; Food, Allergic
Other: Zataria multiflora Boiss
Other: Sumac

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Double Blind (Subject, Investigator)

Further study details as provided by Tehran University of Medical Sciences:

Primary Outcome Measures:
  • Thermic Effect of Food (TEF) [ Time Frame: Change from baseline to 4 hours And repeated 1 week later ] [ Designated as safety issue: No ]
    kilocalorie(kcal) and by indirect calorimetery


Secondary Outcome Measures:
  • activity of sympathetic - parasympathetic system(Epinephrine, Norepinephrine, Cortisol) [ Time Frame: Change from baseline to 4 hours And repeated 1 week later ] [ Designated as safety issue: No ]
    ng/ml


Estimated Enrollment: 40
Study Start Date: August 2012
Estimated Study Completion Date: August 2014
Estimated Primary Completion Date: August 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
sumac
Thermic effect of food of Sumac and comparison between hot and cold temperament people
Other: Sumac
Thermic effect of food of Sumac and comparison between hot and cold temperament people
Other Name: sumach
Zataria multiflora Boiss
Thermic effect of food of Zataria multiflora Boiss and comparison between hot and cold temperament people
Other: Zataria multiflora Boiss
Thermic effect of food of Zataria multiflora Boiss and comparison between hot and cold temperament people
Other Name: Thyme

Detailed Description:

Human body needs to energy in order to preserve life.There are three forms of energy consumption at body, consumption at baseline or resting, consumption at energy expenditure for Thermic effect of food and energy is spent in physical activity.Also from the perspective of traditional medicine, cold and warm natured people are determined based on certain mental and physical protests.

There are different temperament not only in Traditional Iranian Medicine, but in traditional Chinese medicine, Indian, Greek, Arabic, Romanian, and there are European.As various factors on the basal metabolism and thermic effect of food , also are several factors such as age, sex, physical condition of the environment that have an impact on individual temperament.

Since the protests seem warm and cool temperament and factors affecting on their basal metabolic rate and thermogenesis so that food may explain the relationship between warm and cold temperament to mind is the basal metabolism; It seems those are hot temperament, their basal metabolic rate is higher BMR than normal and those who are cold temperament, have a lower BMR.

On the other hand seems that thermic effect of food in people who have hot temperament is higher than thermic effect of food in people who have cold temperament.

So that we need to use of two nutrient foods, in this way we consided the multiple criteria and then were selected sumac and thyme.

On the other hand, in order to study possible mechanisms affecting basal metabolism, thermogenesis of food, according to previous studies and also matches that there are between sympathetic - parasympathetic and thyroid function, with symptoms of cold and warm temperament there, checking of activity of these organs seems necessary.

Because to maintain basal metabolic rate is essential for human life, so that each factor in order to better understand these is helpful to human life.And the need for such study makes clear;Through this step help toward improving public health

  Eligibility

Ages Eligible for Study:   18 Years to 40 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion criteria:

  • Age 18 to 40 years
  • Having to suffer any ill health and lack of attention to history and physical examination
  • Willing to cooperate with the project

Exclusion Criteria:

  • Catching any disease.
  • Use of specific dietary patterns such as vegetarianism
  • Having a BMI outside the normal range
  • Use of any drugs or supplements in past month
  • Allergic reaction to food allergy and non-prescription
  • An unwillingness to cooperate in any of the stages of implementation
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01643096

Locations
Iran, Islamic Republic of
Tehran University of Medical Sciences Not yet recruiting
Tehran, Iran, Islamic Republic of
Contact: Dorosty Motlagh, PhD    (+98) 21 88951395    dorostim@sina.tums.ac.ir   
Contact: Mohammadi Farsani    (+98) 21 88974462    mohammadigh53@gmail.com   
Sponsors and Collaborators
Tehran University of Medical Sciences
Investigators
Principal Investigator: Ahmadreza Dorosty Motlagh, PhD Tehran University of Medical Sciences, tehran, iran
  More Information

No publications provided

Responsible Party: Tehran University of Medical Sciences
ClinicalTrials.gov Identifier: NCT01643096     History of Changes
Other Study ID Numbers: 90-04-27-15366
Study First Received: July 15, 2012
Last Updated: July 16, 2012
Health Authority: Iran: Ethics Committee
Iran: Ministry of Health

Keywords provided by Tehran University of Medical Sciences:
Zataria multiflora Boiss Sumac TEF temperament

ClinicalTrials.gov processed this record on September 16, 2014