Complete Infarct Related Artery Revascularization in Acute Myocardial Infarction (CORAMIreg)

• Death [ Time Frame: At 12 months ] [ Designated as safety issue: Yes ]
  Death rates at 12-month clinical follow-up
  
  
• Stent thrombosis [ Time Frame: At 12 months ] [ Designated as safety issue: Yes ]
  Rates of stent thrombosis at 12-month follow-up according to ARC definition
  
  
• reMI (repeat myocardial infarctions) [ Time Frame: At 12 months ] [ Designated as safety issue: Yes ]
  Rates of reMI at 12 months
  
  
• urgent TVR (target vessel revascularization) at 12 months [ Time Frame: 12 months and at 12 months ] [ Designated as safety issue: Yes ]
  Rates of urgent TVR at 12 months
  
  
• Planned TVR [ Time Frame: At 12 months ] [ Designated as safety issue: Yes ]
  Rates of planned TVR (PCI + CABG) at 12 months
  
  

• Angiographic complications [ Time Frame: During hospitalization ] [ Designated as safety issue: Yes ]
  Immediate in-hospital angiographic complications (at least one or more of the following: distal embolisation, no-reflow, slow-flow, acute coronary artery occlusion, artery perforation, tamponade, dissection type B and above)
  
  
• Target Vessel Revascularization (PCI and/or CABG (coronary artery bypass graft)) [ Time Frame: During hospitalization and at 12 months ] [ Designated as safety issue: Yes ]
  Urgent in-hospital Target Vessel Revascularization (PCI and/or CABG)
  
  
• Complete contrast dose in ml [ Time Frame: During hospitalization and at 12 months ] [ Designated as safety issue: No ]
  Complete contrast dose in ml
  
  
• Complete radiation dose in mGy [ Time Frame: During hospitalization and at 12 months ] [ Designated as safety issue: No ]
  Complete radiation dose in mGy
  
  

CORAMI is a registry study addressing the issue of complete vs culprit-only PCI within infarct related artery in patients with ST-elevation and non-ST elevation myocardial infarction treated with interventional procedures.

The main objectives of the study include:

1. gathering data on patients with at least two independent critical stenotic lesions in IRA (one of which is the culprit lesion) during index primary PCI for STEMI or NSTEMI (prevalence, characteristic, predisposing factors).
2. comparing chosen treatment strategies for multiple lesion IRA
3. comparison of complete vs. target lesion-only PCI in IRA in acute MI (myocardial infarction) patients.

The study clinical hypothesis is that stenting single critical - culprit lesion in multi-lesion IRA in MI patients during index PCI procedure is superior to stenting all critical lesions in IRA in terms of early treatment result and might be associated with less frequent periprocedural angiographic complications.

H0: The efficacy in terms of early treatment result of stenting one critical - culprit lesion in multilesions IRA in acute MI patients is less or equal to efficacy of stenting all critical lesions in IRA.

H1: The efficacy in terms of early treatment result of stenting one critical - culprit lesion in multilesions IRA in acute MI patients is greater than efficacy of stenting all critical lesions in IRA.

CORAMI Registry is a prospective, international (Poland, Slovenia), multicenter observational study with retrospective chart review which will be performed in experienced invasive facility centres with 24/7 PCI duty and continuous patient enrollment for 18 months (January 2011 - June 2012).

This study will collect data on all consecutive patients with STEMI and NSTEMI undergoing immediate coronary angiography which demonstrated at least two independent (requiring two stent platforms) critical lesions in infarct related artery (one of which is considered as target/culprit lesion that have caused the myocardial infarction and requires immediate PCI). Patients will be treated (multiple or single lesion stenting) according to local standard and operator's decision. Patient follow up phone call and/or visit (according to local protocols) will be performed at 12 months from enrollment if applicable by local standards.