Histological Change of The Dentinal-Pulp Complex and Root Resorption

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Paula Villa M, Universidad de Antioquia
ClinicalTrials.gov Identifier:
NCT01642693
First received: July 13, 2012
Last updated: July 16, 2012
Last verified: July 2012
  Purpose

The purpose of the study is evaluate the histological changes of the dentinal-pulp complex and root resorption in maxillary premolars with intrusive orthodontic movement under a low power laser effects.


Condition Intervention Phase
Laser
Intrusion
Histology
Resorption
Radiation: Low power laser in teeth after intrusive movement
Other: Simulated laser in teeth with intrusive movements
Phase 1
Phase 2

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Investigator)
Primary Purpose: Basic Science
Official Title: Histological Changes of The Dentinal-Pulp Complex and Root Resorption in Maxillary Premolars With Intrusive Orthodontic Movements Under a Low Power Laser Effect

Further study details as provided by Universidad de Antioquia:

Primary Outcome Measures:
  • Teeth with intrusive movement and low power laser [ Time Frame: 12 weeks ] [ Designated as safety issue: Yes ]
    Histological changes and root resorption were assesed in Teeth with intrusive movement after a low power laser application


Secondary Outcome Measures:
  • Teeth with intrusive movements with no laser exposition [ Time Frame: 12 weeks ] [ Designated as safety issue: Yes ]
    Histological changes and root resorption were assesed in Teeth with intrusive movement with no laser exposition


Enrollment: 34
Study Start Date: June 2006
Study Completion Date: May 2009
Primary Completion Date: May 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Teeth with intrusive movement and low power laser
Histological changes and root resorption were assesed in Teeth with intrusive movement after a low power laser application
Radiation: Low power laser in teeth after intrusive movement
Low power laser was aplied to premolar teeth under an intrusive movement to study histological changes and root resorption
Experimental: Teeth with intrusive movements with no laser
Histological changes and root resorption in Teeth with intrusive movements with no laser
Other: Simulated laser in teeth with intrusive movements
Simulated laser in teeth with intrusive movements for histological and root resorption changes

Detailed Description:

Orthodontics movements can cause inflamatory changes in the pulp and external inflamatory root resorption, different methods have been suggested to control that changes as the use of the low power laser. The objective of this study is to evaluate the low power laser effect on the inflamatory pulpar change and inflamatory external root resorption in maxillary premolars with intrusive orthodontic movements of 4 ounces during 12 weeks. Total sample were 34 healthy teeth, 16 were used to evaluate the normal standar and 18 were divided in two groups, the experimental group with the low power laser effect had a dose of 18 joules after activations of the orthodontic intrusion and the control group had a simulated effect in the same orthodontic movement. Teeth were extacted after 12 weeks and histological changes were evaluated in the dentinal-pulp complex and the pesence of external inflamatory root resorption. Findins suggest that low power. Laser decreased the inflamatory changes of the dentinal - pulp complex and the severity of the external inflamatory root resorption.

  Eligibility

Ages Eligible for Study:   13 Years to 23 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Patients with first premolar extraction indicated
  • Patients with no sistemic diseases
  • Healthy premolars with completed root and no trauma or restoration

Exclusion Criteria:

  • Sistemics diseased
  • Restoration, trauma in first premolars
  • root uncompleted
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01642693

Locations
Colombia
Paula Villa M
Medellin, Antioquia, Colombia, 00000
Sponsors and Collaborators
Universidad de Antioquia
  More Information

No publications provided

Responsible Party: Paula Villa M, Partial time proffesor in Endodontics, Universidad de Antioquia
ClinicalTrials.gov Identifier: NCT01642693     History of Changes
Other Study ID Numbers: 2006-007
Study First Received: July 13, 2012
Last Updated: July 16, 2012
Health Authority: Colombia: National Institutes of Health

Keywords provided by Universidad de Antioquia:
root resorption
low-power laser
orthodontic tooth movement
pulp changes

Additional relevant MeSH terms:
Root Resorption
Tooth Resorption
Tooth Diseases
Stomatognathic Diseases

ClinicalTrials.gov processed this record on September 18, 2014