Preoperative Gabapentine for Carpal Tunnel
The purpose of this study was to evaluate the postoperative analgesic effect of preoperative gabapentine for carpal tunnel syndrome surgery.
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:||Effect of Preoperative Gabapentine for Carpal Tunnel Syndrome|
- Pain Intensity [ Time Frame: 6 months ] [ Designated as safety issue: No ]Numerical score from 0 to 10; zero means no pain and 10 is the more intense pain
- Chronic Pain [ Time Frame: 6 months ] [ Designated as safety issue: No ]Number of neuropathic pain and complex regional syndrome pain after 6 months
|Study Start Date:||March 2010|
|Study Completion Date:||March 2012|
|Primary Completion Date:||August 2011 (Final data collection date for primary outcome measure)|
Experimental: preoperative gabapentine,
Gabapentine 600 mg 01 dose
Other Name: Anticonvulsant
Placebo Comparator: sugar pill
Other: Sugar pill
Sugar pill 01 dose
There was studied 40 patients. Group 1 patients received 600 mg of gabapentin 1 hour before surgery; G2 received placebo 1 hour before surgery.
Anesthesia was regional intravenous block. Postoperative analgesia when needed was with acetaminophen. If needed was administered codeine. The evaluation of neuropathic pain was made by DN4 questionnaire. Pain intensity was assessed by numeric scale at block and after 30min, 1h, 2h, 2wk, 4wk, 6m. It was noted the duration of analgesia, and the amount of acetaminophen and codeine.
The statistical program used for analysis of the results was the Instat Graph
Please refer to this study by its ClinicalTrials.gov identifier: NCT01632215
|Study Director:||Rioko K Sakata, PhD||Universidade Federal de São Paulo|