A Trial of an Oral Nutritional Supplement in Older Hospitalized Patients

Inclusion Criteria:

1. Male or female ≥ 65 and < 95 years of age.
2. Admitted to hospital with diagnosis of heart failure, acute myocardial infarction, pneumonia, or chronic obstructive pulmonary disease.
3. Subjective Global Assessment rating of B or C.
4. Length of hospital stay anticipated to be > 3 days and < 12 days
5. Able to consume foods and beverages orally.
6. Functionally ambulatory during the 30 days prior to admission.
7. Has not had a hospital admission in the past 30 days.

Exclusion Criteria

1. Requires intensive care unit admission.
2. Uncontrolled hypertension
3. Diagnosis of diabetes
4. Current active cancer or recently treated cancer
5. Impaired renal function
6. Liver failure, acute Hepatitis, or hepatic encephalopathy
7. Active tuberculosis.
8. HIV
9. Disorder of gastrointestinal tract
10. Autoimmune disorder
11. Severe COPD
12. Intubation, and/or tube or parenteral feeding.
13. Expected to be transferred for to an advanced care unit within 3 days.
14. Severe dementia or delirium, brain metastases, eating disorder, history of significant neurological or psychiatric disorder, alcoholism, substance abuse or other conditions that may interfere with study product consumption or compliance with study protocol procedures
15. Allergy or intolerance to any of the ingredients in the study products.
16. Body mass index of ≥ 40 kg/m2.
17. Resident in a nursing home or other residential facility.