Causes of Visual Loss in Retinal Disease

• Visual acuity at 5 years [ Time Frame: 5 years ] [ Designated as safety issue: No ]
  Best-corrected visual acuity at 5 years
  
  

• Visual acuity at 10 years [ Time Frame: 10 years ] [ Designated as safety issue: No ]
  Best corrected visual acuity at 10 years
  
  
• Source of referral [ Time Frame: Baseline ] [ Designated as safety issue: No ]
  Categorised as A&E/GP referral/Optician referral/Tertiary referral
  
  
• Laterality [ Time Frame: Baseline ] [ Designated as safety issue: No ]

  Categorised as:

  Right eye/Left eye/Bilateral

  
  
• Anatomical diagnosis [ Time Frame: Baseline ] [ Designated as safety issue: No ]

  Cateogorised as:

  Acute anterior uveitis / Chronic anterior uveitis / Fuchs heterochromic cyclitis / Intermediate uveitis / Pars planitis / Posterior Uveitis / Panuveitis / Episcleritis / Scleritis

  
  
• Aetiological diagnosis [ Time Frame: Baseline ] [ Designated as safety issue: No ]

  Diagnosed as:

  Viral / Bacterial / Fungal / Parasitic / Inflammatory / Malignant

  
  
• Associated systemic disease [ Time Frame: Baseline ] [ Designated as safety issue: No ]
  Any associated systemic disease, e.g. HLA-B27 associated disease, Behcet's disease, multiple sclerosis, Vogt-Koyanagi-Harada syndrome, rheumatoid arthritis, collagen vascular disease, tuberculosis, granulomatosis with polyangiitis
  
  
• Complications of disease and causes of visual loss at 5 years [ Time Frame: 5 years ] [ Designated as safety issue: No ]

  Categorised into:

  Corneal clarity problems / cataract / vitreous debris / retinal detachment / cystoid macular edema / retinal pigment epithelium atrophy / macular scarring / epiretinal membrane / macular hole / steroid response / glaucoma / other optic neuropathy / hypotony & phthisis / other

  
  
• Complications of disease and causes of visual loss at 10 years [ Time Frame: 10 years ] [ Designated as safety issue: No ]

  Categorised into:

  Corneal clarity problems / cataract / vitreous debris / retinal detachment / cystoid macular edema / retinal pigment epithelium atrophy / macular scarring / epiretinal membrane / macular hole / steroid response / glaucoma / other optic neuropathy / hypotony & phthisis / other

  
  
• Complications of disease and causes of visual loss [ Time Frame: Up to 10 years ] [ Designated as safety issue: No ]

  Categorised into:

  Corneal clarity problems / cataract / vitreous debris / retinal detachment / cystoid macular edema / retinal pigment epithelium atrophy / macular scarring / epiretinal membrane / macular hole / steroid response / glaucoma / other optic neuropathy / hypotony & phthisis / other

  
  
• Treatment measures employed [ Time Frame: Up to 10 years ] [ Designated as safety issue: No ]

  Categorised into:

  Topical treatment / periocular steroid / intraocular steroid / intraocular other agent / Glaucoma treatment / systemic immunosuppressive agents

  
  
• Complications of disease and treatment [ Time Frame: Up to 10 years ] [ Designated as safety issue: No ]

  Categorised into:

  1. Local complications: Raised intraocular pressure / cataract / endophthalmitis / other
  2. Systemic complications: Diabetes / hypertension / cholesterol / liver function / bone density loss / other
  
  
• Surgical procedures [ Time Frame: Up to 10 years ] [ Designated as safety issue: No ]
  List and dates of any intraocular surgery performed during the study
  
  
• Burden of disease - appointments [ Time Frame: Up to 10 years ] [ Designated as safety issue: No ]
  Number of outpatient appointments over the course of the study
  
  
• Burden of disease - outpatient procedures [ Time Frame: Up to 10 years ] [ Designated as safety issue: No ]
  Number of outpatient procedures over the course of the study
  
  
• Burden of disease - inpatient procedures [ Time Frame: Up to 10 years ] [ Designated as safety issue: No ]
  Number of inpatient procedures over the course of the study
  
  
• Blind registration [ Time Frame: Up to 10 years ] [ Designated as safety issue: No ]
  Year of any registration as partially sighted or blind
  
  

This is a study of visual outcomes in retinal disease. It is an observational study of patients who have been seen in the retinal clinic, and involves a retrospective casenotes analysis to identify patients who have suffered visual loss and the reason for that visual loss. These data will be analysed to enable the identification of factors that predict visual loss in patients who present earlier in the course of their disease.