Measurement of Cardiac Output and Intravascular Volume Status in Children Using COstatus (SH)
Assessment and monitoring of cardiac function in the pediatric intensive care unit (PICU) is an integral part of hemodynamic monitoring of critically ill patients whether it is done directly or indirectly. Measurement of cardiac output (CO) can specifically guide therapies to support the cardiovascular system in critically ill children with multi organ dysfunction. Because of the side effects involved in measuring cardiac output directly, intensive monitoring of patients is currently limited to an integrated assessment of tissue perfusion, oxygen delivery and cellular health both at regional and global levels. Currently available methods of measuring CO have their limitations and complications, and are not used routinely for bedside monitoring. Therefore, the investigators propose to use a newly developed method, termed COstatus for the monitoring of CO in patients admitted to PICU.
|Study Design:||Time Perspective: Prospective|
|Official Title:||Measurement of Cardiac Output and Intravascular Volume Status in Critically Ill Children Using an Ultrasound Dilution Method (COstatus)|
- Comparing CO and other clinical markers in Pediatric ICU [ Time Frame: During patients stay in ICU with insitu catheter, expected average 3-4 days ] [ Designated as safety issue: No ]The objective of this study is to see if the CO measurements obtained with COstatus show a linear correlation with all other indirect and invasive methods currently used to measure CO (within acceptable range) and with the CO measured by thermodilution in the cardiac catheterization lab.
|Study Start Date:||January 2012|
|Estimated Study Completion Date:||December 2014|
|Estimated Primary Completion Date:||December 2014 (Final data collection date for primary outcome measure)|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01613859
|Contact: Jai Udassi, MDfirstname.lastname@example.org|
|United States, Florida|
|Shands Children's Hospital, University of Florida||Recruiting|
|Gainesville, Florida, United States, 32608|
|Contact: Jai Udassi, MD email@example.com|
|Principal Investigator: Jai Udassi, MD|
|Principal Investigator:||Jai Udassi, MD||Shands Children's Hospital, University of Florida|