Text Size

Clinical Characteristics of Allergy, Autoimmune and Rheumatic Diseases: A Ten Year Retrospective Study

This study is currently recruiting participants.
Verified June 2012 by Far Eastern Memorial Hospital
Sponsor:
Information provided by (Responsible Party):
Chien-Sheng Wu, Far Eastern Memorial Hospital
ClinicalTrials.gov Identifier:
NCT01611636
First received: May 26, 2012
Last updated: June 4, 2012
Last verified: June 2012
History of Changes
  Purpose

The incidence and prevalence of the allergic, autoimmune and rheumatic diseases are different all over the world. The relative impact of gene and environment on diseases can be revealed by studies from different populations. National Health Insurance database in Taiwan provides a wealth of epidemiology study, which can contribute to the understanding of these diseases. However, national health care database did not contain test results and clinical details. The database of the hospital records can provide complimentary clinical details. Via the comparison of databases of the National health Institutes and the investigators hospital, the investigators hope that the characteristics and outcomes of these patients can be better understood.


Condition
Allergy
Autoimmune Diseases
Rheumatic Diseases

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Clinical Characteristics of Allergy, Autoimmune and Rheumatic Diseases: A Ten Year Retrospective Study

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Far Eastern Memorial Hospital:

Primary Outcome Measures:
  • Incidence of target diseases [ Time Frame: Up to ten years ] [ Designated as safety issue: No ]
    Population at risk of target diseases in database will be assessed up to 10 years


Estimated Enrollment: 200000
Study Start Date: January 2012
Estimated Study Completion Date: January 2022
Estimated Primary Completion Date: January 2022 (Final data collection date for primary outcome measure)
Detailed Description:

The incidence and prevalence of the allergic, autoimmune and rheumatic diseases are different all over the world. The relative impact of gene and environment on diseases can be revealed by studies from different populations.

National Health Insurance database in Taiwan provides a wealth of epidemiology study, which can contribute to the understanding of these diseases. However, national health care database did not contain test results and clinical details. The database of the hospital records can provide complimentary clinical details. Via the comparison of databases of the National health Institutes and the investigators hospital, the investigators hope that the characteristics and outcomes of these patients can be better understood.

Briefly, epidemiology of target disease such as age, sex, incidence and prevalence will be derived from national database. Medical source utilization such as medication and surgery related to target diseases is also available in national database, providing material for cost analysis. These data can be compared with hospital database to ensure validity and reliability.

The investigators study is intended to provide epidemiology of target disease and cost analysis. Interaction between diseases will also be explored.

Target diseases Allergic diseases: Asthma(ICD9 493.x),Steven-Johnson syndrome and other erythroderma (ICD9 695.x)

Autoimmune diseases: Thyroid disease (ICD9 246.x), Addison disease (ICD9 255.x), type 1 diabetes mellitus (250.x1)

Rheumatic diseases: gout (ICD9 274.x), SLE (ICD9 710.0 ), RA (ICD9 714.0), AS and spondylitis (ICD9 720.0&720.x), Psoriasis and psoriatic arthritis (ICD9 696.0), scleroderma (ICD9 710.1), Sjogren's syndrome (ICD9 710.2), dermatomyositis (ICD9 710.3), polymyositis (ICD9 710.4), ANCA vasculitis (WG 446.4, MPA, CSS, PAN ICD9 446.0) or vasculitis 447.6, Behcet's disease(ICD9 136.1), Temporal arteritis(ICD9 446.5), Takayasu arteritis (ICD9 446.7), Henoch-Schonlein purpura (ICD9 287.0)

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

National Health Insurance Research Database Far Eastern Memorial Hospital clinical database

Criteria

Inclusion Criteria:

  • subjects with ICD9 coding fulfilling study subjects
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01611636

Locations
Taiwan
Far Eastern Memorial Hospital Recruiting
New Taipei City, Taiwan, 220
Contact: ChienSheng Wu, Master     886931070043     wucs@mail.femh.org.tw    
Principal Investigator: ChienSheng Wu, Master            
Sponsors and Collaborators
Far Eastern Memorial Hospital
Investigators
Principal Investigator: ChienSheng Wu, Master Chief, Department of Rheumatic disease
  More Information

No publications provided

Responsible Party: Chien-Sheng Wu, Chief, Division of Rheumatology, Far Eastern Memorial Hospital
ClinicalTrials.gov Identifier: NCT01611636     History of Changes
Other Study ID Numbers: 100165-E
Study First Received: May 26, 2012
Last Updated: June 4, 2012
Health Authority: Taiwan: Department of Health

Keywords provided by Far Eastern Memorial Hospital:
allergy
autoimmune diseases
rheumatic diseases

Additional relevant MeSH terms:
Hypersensitivity
Autoimmune Diseases
Rheumatic Diseases
 Immune System Diseases
Musculoskeletal Diseases
Connective Tissue Diseases

ClinicalTrials.gov processed this record on May 16, 2013