Physical Activity, Health and Age
Ageing is associated with a reduction of physical activity, movement efficiency, and quality of sleep. This leads to reduced health and well being in elderly subjects. Exercise training can increase movement efficiency and quality of sleep.
- Laboratory validation test of body acceleration based indexes for movement efficiency and quality of sleep;
- Cross-sectional analysis to assess relations between these indexes and age;
- Intervention study to assess the effect of exercise training on daily life movement efficiency and quality of sleep in ageing subjects
The population will be composed of 100 healthy human volunteers, age 45-85 yr, BMI 20-30 kg/m2, 25 subjects in each decade. Twenty subjects, five per decade, will be part of a control group. Subjects that will have practiced fitness activities in the previous year, as well as pregnant or lactating women, will be excluded.
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Factorial Assignment
Masking: Open Label
Primary Purpose: Basic Science
|Official Title:||Physical Activity and Movement Efficiency and Quality of Sleep With Increasing Age|
- Changes in daily life movement efficiency [ Time Frame: Baseline, at 6 months and after 1 year ] [ Designated as safety issue: No ]
The primary objective is to identify features of body acceleration to be included in an index to assess daily life movement efficiency. Secondly, the index is related with age to quantify how ageing affects daily life movement efficiency.
The third objective is to show the effects of regular physical activity training on this index. The expected improvement of the index would show that exercise delays the age related decrease of movement efficiency.
- Changes in daily life quality of sleep [ Time Frame: Baseline, at 6 months and after 1 year ] [ Designated as safety issue: No ]
The primary objective is to identify features of body acceleration to be included in one index to assess quality of sleep in daily life. Secondly, the index is related with age to quantify how ageing affects quality of sleep.
The third objective is to show the effects of regular physical activity training on this index. The expected improvement of the index would show that exercise delays the age related decrease of quality of sleep.
|Study Start Date:||July 2012|
|Estimated Primary Completion Date:||October 2015 (Final data collection date for primary outcome measure)|
Follows the fitness program as described in the intervention
Behavioral: One year fitness training
Regular training schedule of moderate intensity, at 50% of heart rate reserve, as available for the specific age group in fitness centres
No Intervention: Control
Will not follow any regular fitness activity during one year
|Contact: Giulio Valenti, drs||+31(0)4338 82 firstname.lastname@example.org|
|Maastricht University||Not yet recruiting|
|Maastricht, Limburg, Netherlands, 6200 MD|
|Sub-Investigator: Giulio Valenti, drs|
|Principal Investigator: Klaas R Westerterp, Professor|
|Principal Investigator:||Klaas R Westerterp, Professor||Maastricht University, NUTRIM, Human biology|