Risk Factor Analysis for Coronary Atherosclerosis Measured by MDCT
The recruitment status of this study is unknown because the information has not been verified recently.
Verified April 2012 by Korea University.
Recruitment status was Recruiting
Information provided by (Responsible Party):
K. M. Choi, Korea University
First received: April 24, 2012
Last updated: May 7, 2012
Last verified: April 2012
Coronary MDCT (multi-detector computed tomography) has been useful screening imaging modality for the coronary artery disease. Recently, novel adipokines and hepatokines as well as various inflammatory markers have been known as direct regulators of atherosclerosis. Therefore, the investigators examine the correlation of various metabolic risk factors including adipokines and hepatokines with coronary atherosclerosis measured by coronary MDCT in apparently healthy people.
||Observational Model: Cohort
Time Perspective: Prospective
Primary Outcome Measures:
- relation of adipokines and hepatokines with coronary atherosclerosis measured by MDCT [ Time Frame: 3month ] [ Designated as safety issue: No ]
to examine the correlation of serum concentration of various adipokine such as adiponectin, resistin, A-FABP with coronary atheroslcerosis measured by MDCT as AGATSTON score, modified Gensini score
Secondary Outcome Measures:
- relation of adipokines and hepatokines with coronary atherosclerosis measured by MDCT [ Time Frame: 3months ] [ Designated as safety issue: No ]
to examine the correlation of serum concentration of various hepatokines such as FGF-21, fetuin- A and selenoprotein P with coronary atheroslcerosis measured by MDCT as AGATSTON score, modified Gensini score
- the correlation of various inflammatory markers with coronary atherosclerosis [ Time Frame: 3months ] [ Designated as safety issue: No ]
| Estimated Enrollment:
| Study Start Date:
| Estimated Primary Completion Date:
||August 2012 (Final data collection date for primary outcome measure)
|Ages Eligible for Study:
||20 Years to 80 Years
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Apparently healthy people who underwent medical routine check up in Korea Helath Promotion Center.
- Apparently healthy people who underwent medical routine check up in Korea Health Promotion Center.
- age > 20 years
- History of cardiovascular disease (myocardial infarction, unstable angina, stroke, or cardiovascular revascularization)
- Stage 2 hypertension
- Severe renal or hepatic disease
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Please refer to this study by its ClinicalTrials.gov identifier: NCT01589224
|korea University Guro Hospital
|Seoul, Korea, Republic of |
|Contact: Hye Jin Yoo, MD.Ph.D 822-2626-3045 firstname.lastname@example.org |
|Principal Investigator: Kyung Mook Choi, MD.Ph.D |
No publications provided
||K. M. Choi, Professor, Korea University
History of Changes
|Other Study ID Numbers:
|Study First Received:
||April 24, 2012
||May 7, 2012
||South Korea: Institutional Review Board
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on August 01, 2014
Coronary Artery Disease
Metabolic Syndrome X
Arterial Occlusive Diseases
Glucose Metabolism Disorders