Text Size

Real-Time fMRI Feedback Effects on Pain Perception

This study is ongoing, but not recruiting participants.
Sponsor:
Information provided by (Responsible Party):
Medical University of South Carolina
ClinicalTrials.gov Identifier:
NCT01588197
First received: February 10, 2012
Last updated: April 26, 2012
Last verified: April 2012
History of Changes
  Purpose

The purpose of this study is to determine whether real-time functional magnetic resonance imaging may be a viable treatment for chronic pain in the future.


Condition Intervention
Cognitive Pain Control
 Behavioral: MRI Feedback

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Official Title: Real-Time fMRI Feedback Effects on Pain Perception

Further study details as provided by Medical University of South Carolina:

Primary Outcome Measures:
  • RT-fMRI enhancement of the effects of cognitive pain control strategies [ Time Frame: Participants will be monitored for the duration of the study visit, with an expected average of 2 hours. ] [ Designated as safety issue: No ]
    Activation of Prefrontal Cortex and rACC from fMRI images


Secondary Outcome Measures:
  • Effectiveness of cognitive pain modulation techniques [ Time Frame: Participants will be monitored for the duration of the study visit, with an expected average of 2 hours. ] [ Designated as safety issue: No ]
    subjective verbal pain ratings and thermal pain thresholds


Estimated Enrollment: 30
Study Start Date: November 2010
Primary Completion Date: April 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: PreFrontal Cortex Behavioral: MRI Feedback
Real Time fMRI Feedback
Experimental: Anterior Cingulate Behavioral: MRI Feedback
Real Time fMRI Feedback

  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Healthy adults ages 18-65

Exclusion Criteria:

  • Clinical depression
  • Anxiety
  • Substance dependence or chronic pain
  • Ferrous metal implants
  • Cardiac pacemakers or other implanted medical devices that might be adversely impacted by the MRI scanner magnetic field
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01588197

Locations
United States, South Carolina
Medical University of South Carolina
Charleston, South Carolina, United States, 29425
Sponsors and Collaborators
Medical University of South Carolina
Investigators
Principal Investigator: Jeffery J Borckardt, PhD Medical University of South Carolina
  More Information

No publications provided

Responsible Party: Medical University of South Carolina
ClinicalTrials.gov Identifier: NCT01588197     History of Changes
Other Study ID Numbers: HR # 20270
Study First Received: February 10, 2012
Last Updated: April 26, 2012
Health Authority: United States: Institutional Review Board

Keywords provided by Medical University of South Carolina:
Pain
fMRI
real time

ClinicalTrials.gov processed this record on May 16, 2013