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Evaluation of Platelet Rich Fibrin on Reduction of Periodontal Problems After Surgical Removal of Mandibular Third Molar

The recruitment status of this study is unknown because the information has not been verified recently.
Verified April 2012 by Mashhad University of Medical Sciences.
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by (Responsible Party):
Majid Eshghpour, Mashhad University of Medical Sciences
ClinicalTrials.gov Identifier:
NCT01583491
First received: December 7, 2011
Last updated: April 24, 2012
Last verified: April 2012
  Purpose

The purpose of this study is to determine the influence of platelet rich fibrin to reduction of periodontal problems after surgical removal of third molar.


Condition Intervention Phase
Mastication Disorder
Procedure: autologous platlet rich fibrin
Procedure: one side in control group
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Investigator, Outcomes Assessor)
Primary Purpose: Prevention
Official Title: Evaluation of Platelet Rich Fibrin Efficacy on Reduction of Periodontal Problems

Further study details as provided by Mashhad University of Medical Sciences:

Primary Outcome Measures:
  • Measurement of periodontal pocket depth at mid buccal, disto buccal and distolingual of mandibular second molar [ Time Frame: 4 months ] [ Designated as safety issue: Yes ]

Enrollment: 30
Study Start Date: December 2011
Estimated Study Completion Date: May 2012
Estimated Primary Completion Date: April 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: prf group.peridontal problem
prf insert into surgical site immediate after surgery
Procedure: autologous platlet rich fibrin
one dose immediate after surgery
Other Name: prf
Placebo Comparator: control group Procedure: one side in control group
control group insert any things after surgery

Detailed Description:

After extraction or surgical removal of third molar, a deep bony pocket created behind the second molar specially in the mandible. For reduction of this problem, investigators, needed to acceleration tissue healing. For this purpose, investigators used platelet rich fibrin (autologous) and followed patient for 3 months.

  Eligibility

Ages Eligible for Study:   18 Years to 35 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • have 2 impacted third molars

Exclusion Criteria:

  • periodontal disease
  • history of periodontal surgery
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

No Contacts or Locations Provided
  More Information

No publications provided

Responsible Party: Majid Eshghpour, assistant professor, Mashhad University of Medical Sciences
ClinicalTrials.gov Identifier: NCT01583491     History of Changes
Other Study ID Numbers: 900093
Study First Received: December 7, 2011
Last Updated: April 24, 2012
Health Authority: Iran: Ethics Committee

Keywords provided by Mashhad University of Medical Sciences:
platelet rich fibrin
mandibular third molar
periodontal problem

ClinicalTrials.gov processed this record on November 25, 2014