Exercise Study in Patients With Lung Cancer (POSITIVE)

• - number of patients who are adherent to the exercise intervention [ Time Frame: 8 months ] [ Designated as safety issue: Yes ]
  Adherence is defined as: completion of at least two training sessions per week during minimum six weeks out of eight weeks of the intervention.
  
  

• - effects of the exercise intervention on psychological symptoms (e.g. quality of life) [ Time Frame: 8 months ] [ Designated as safety issue: Yes ]
  Quality of life will be measured by the standardized and validated questionnaire FACT-L;
  
  
• - effects of the exercise intervention on physical symptoms (muscle strength and endurance) [ Time Frame: 8 months ] [ Designated as safety issue: Yes ]
  Muscle strength will be measured by hand held dynamometry and endurance by 6 Minute Walk Test
  
  

In this open, prospective, single center study 40 patients (pts) with NSCLC undergoing adjuvant or palliative chemo-/ or radiotherapy are enrolled. Physical status is assessed by using the 6 Minute Walk Test (6MWT) for endurance and by using the Handheld Dynamometer (HHDM) for strength (flexion and extension of elbow, hip and knee). Psychological performance is measured by standardized questionnaires (MFI, FACT-L, PHQ - 9). Data are collected at baseline (T0) and after the 8 weeks sports intervention (T1). Pts are instructed to train at least 5 times/ week in the inpatient setting. After discharge pts are instructed to train in a home-based setting at least 3 times/week for a period of 8 weeks. Feasibility is defined as an adherence of two trainings per week during at least 6 weeks (out of 8 weeks of the intervention).