A Comparative Study of Effects of Berry and Grain Products on Postprandial Glycemic Response in Healthy Subjects
This study aims to determine the 2 hour glycemic responses of two bread products and one dried lingonberry product. The average postprandial response of each product is compared with glycemic response after ingestion of control solution with a similar carbohydrate content (glucose, glucose-fructose) as the provided by the respective test product.
Other: Berry product
Other: Bread product
Other: Glucose control solution
Other: Glucose-fructose control solution
|Study Design:||Intervention Model: Single Group Assignment
Masking: Open Label
|Official Title:||A Clinical, Randomized, Comparative Study of Effects of Berry and Grain Products on Postprandial Glycemic Response in Healthy Subjects|
- The 2 hours glycemic responses to test products and control solutions [ Time Frame: 2 hours ] [ Designated as safety issue: No ]Capillary blood samples are taken before and at 15, 30, 45, 60, 90 and 120 min after starting to eat the test products or control solutions for measurements of plasma glucose concentrations.
- The 2 hours insulinemic responses to dried lingonberry product and corresponding control solution [ Time Frame: 2 hours ] [ Designated as safety issue: No ]Capillary blood samples are collected before and at 15, 30, 45, 60, 90 and 120 min after eating the lingonberry test product and glucose-fructose control solution. The serum insulin concentrations are analysed.
- The incremental area under glucose curve (IAUC) of bread test products [ Time Frame: 2 hours ] [ Designated as safety issue: No ]IAUC (mmol/l x min) is determined using the trapezoidal method for each subject and bread test product and corresponding glucose control solution.
- Glycemic index (GI) of bread test products [ Designated as safety issue: No ]The GI is calculated as a percentage of the glucose IAUC values of a bread product and a glucose control solution.
|Study Start Date:||March 2012|
|Study Completion Date:||June 2012|
|Primary Completion Date:||June 2012 (Final data collection date for primary outcome measure)|
Other: Berry product
Please refer to this study by its ClinicalTrials.gov identifier: NCT01575509
|Clinical Life Sciences Ltd|
|Kajaani, Finland, 87100|
|Principal Investigator:||Päivi Cheney, MD|