Investigation of a Novel Gene Expression Test for the Diagnosis of Obstructive Coronary Artery Disease on Physician's Practice Pattern

• Rate of referral vs. Corus score as continuous variables [ Time Frame: 30 Days ] [ Designated as safety issue: No ]
  Composite endpoint consisting of referrals to a cardiologist, to cardiac stress/CTA and/or to invasive cardiac catheterization occurring between Day 0 and Day 30 + 15 days.
  
  

• Rate of referral difference between low Corus (</=15) and non-low Corus (>15) scores. [ Time Frame: 30 Day ] [ Designated as safety issue: No ]
  composite endpoint consisting of referrals to a cardiologist, to cardiac stress/CTA, and/or referral to invasive cardiac catheterization at Day 30 +15 days.
  
  

Objective of the study is to assess whether the score provided by the CORUS® CAD test has an effect on the Primary Care Physician's patient management and referral patterns once received:

1. no further cardiac testing or treatment
2. medical therapy for angina or non-cardiac chest pain
3. Referral to a cardiologist for stress testing with or without imaging, CT angiography, or invasive cardiac catheterization.

Since it takes approximately two days for the physician to receive the result of the CORUS CAD, initial diagnostic testing will reflect local standard of care