Changes of Endothelial Function Before and After DSA in Patients With Diabetes
Endothelial dysfunction is the early step of atherosclerosis. Therefore, the investigators hypothesize that digital subtraction angiography (DSA) can damage endothelial function. In this study, the investigators will select 200 diabetic patients who have a DSA for diabetic foot screening. Also, the investigators will select 100 healthy subjects as controls. The endothelial function will be determined by high resolution ultrasound before and after DSA. The investigators will observe the changes of endothelial function after DSA assay.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Changes of Endothelial Function Before and After DSA in Patients With Diabetes|
- The changes of endothelial function [ Time Frame: 10 months ] [ Designated as safety issue: Yes ]
|Study Start Date:||October 2012|
|Estimated Study Completion Date:||October 2013|
|Estimated Primary Completion Date:||August 2013 (Final data collection date for primary outcome measure)|
Other: DSA assay
All patients with diabetic foot perform a DSA assay. Before and after DSA, endothelial function will be measured.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01556984
|Contact: Xiang Guangda, MD||+862768878410||Guangda64@hotmail.com|
|Wuhan General Hospital||Recruiting|
|Wuhan, Hubei, China, 430070|
|Contact: Yue Ling, MD +862768878410 Yueling@med.mail.com|