Clinical Characteristics, Management and Outcomes of Chinese Patients With Acute Aortic Dissection (CCMOCPAAD)

This study is currently recruiting participants. (see Contacts and Locations)
Verified March 2012 by Xijing Hospital
Sponsor:
Information provided by (Responsible Party):
Yang Li, MD, Xijing Hospital
ClinicalTrials.gov Identifier:
NCT01552720
First received: March 7, 2012
Last updated: March 12, 2012
Last verified: March 2012
  Purpose

Data reported by the international registry of acute aortic dissection (IRAD) in not sufficient to reflect clinical characteristics of acute aortic dissection in China. Moreover, clinical characteristics of Acute aortic dissection have not evaluated to data. The aim of this study is analyze changing trend of clinical characteristics of Chinese patients with acute aortic dissection.


Condition
Aortic Dissection

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: Clinical Investigation of Chinese Patients With Aortic Dissection

Further study details as provided by Xijing Hospital:

Estimated Enrollment: 5000
Study Start Date: January 2011
Estimated Study Completion Date: December 2015
Estimated Primary Completion Date: November 2015 (Final data collection date for primary outcome measure)
Detailed Description:

Acute aortic dissection is the most common aortic emergency, with an annual incidence of 3-5 cases per 100 000 population. About 50% of these patients are dead within 48 hours, if untreated. To assess the clinical manifestation, diagnosis, management, and outcomes of patients with AAD, the International Registry of Acute Aortic Dissection (IRAD) was established in 1996, and has grown to include about 2000 patients from 26 large referral centers to date. All patients from IRAD are caucasians from developed countries wiht advanced medical care, however, the proportion of Asian is very low. Data reported by the IRAD in not sufficient to reflect clinical characteristics of Acute aortic dissection in China. Clinical characteristics of Chinese patients with acute aortic dissection have not evaluated to data. The aim of this study is to analyze clinical characteristics of Chinese patients with acute aortic dissection and clinical trend of acute aortic dissection.

  Eligibility

Ages Eligible for Study:   18 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Chinese patients suffering acute aortic dissection

Criteria

Inclusion Criteria:

  • Clinical diagnosis of acute aortic dissection
  • Type A dissection
  • Type B dissection
  • Retrograde type B dissection

Exclusion Criteria:

  • Aortic aneurysm
  • Myocardial infarction
  • Cerebral accident
  • Active infection
  • Unwillingness to cooperation with study procedures or follow-up visits
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01552720

Contacts
Contact: Yang Li, MD 029-6787564 liyangcenter@sina.com

Locations
China, Shaanxi
Xijing Hospital Recruiting
Xi'an, Shaanxi, China, 710032
Contact: Yang Li, MD    029-68574562    liyangcenter@sina.com   
Principal Investigator: Yang Li, MD         
Principal Investigator: Dinghua Yi, PhD,MD         
Principal Investigator: Weixun Duan, MD         
Sponsors and Collaborators
Xijing Hospital
Investigators
Study Director: Dihua Yi, PhD, MD Xijing Hospital
  More Information

Additional Information:
No publications provided

Responsible Party: Yang Li, MD, MD, Xijing Hospital
ClinicalTrials.gov Identifier: NCT01552720     History of Changes
Other Study ID Numbers: XJHEART2012, CRAD201203
Study First Received: March 7, 2012
Last Updated: March 12, 2012
Health Authority: China: Food and Drug Administration

Keywords provided by Xijing Hospital:
aorta
dissection
feature

ClinicalTrials.gov processed this record on July 24, 2014