Efficacy and Safety of Fractional Carbon Dioxide Laser for Treatment of Facial Freckles.
Recruitment status was Not yet recruiting
Freckles are clusters of melanin in the superficial epidermis. They affect mostly face and sun exposed areas, and appear as flat brown or red macules that fade in winter, usually in a fair complexion patient, but may be present in other skin types.
The gold standard in the industry for non-surgical facial rejuvenation, removal of wrinkles, pigmentation, and general sun damage has been the carbon dioxide (CO2) laser since the mid 1990s. The traditional CO2 laser was very effective, however it fell out of favor because it required general anesthesia. It also had a prolonged recovery time. Over the last several years, advances in technology known as fractional resurfacing has made the CO2 laser popular again: Fractional CO2 laser treatment is one of the newest laser rejuvenation technology. It proved successful in treatment of melasma, one of the pigmented dermatoses. To the best of our knowledge, based on a thorough search of literature, no clinical studies assessing fractional CO2 laser in treatment of freckles could be retrieved.
|Study Design:||Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Efficacy and Safety of Fractional Carbon Dioxide Laser for Treatment of Facial Freckles|
- treatment success [ Time Frame: One month ] [ Designated as safety issue: No ]reduction of freckles number and color density more than 50% in comparison to pre-treatment digital photos
- Treatment safety [ Time Frame: three months ] [ Designated as safety issue: Yes ]Absence of irreversible changes in color and texture of the facial skin, that can cause patient dissatisfaction
|Study Start Date:||March 2012|
|Estimated Study Completion Date:||October 2012|
|Estimated Primary Completion Date:||July 2012 (Final data collection date for primary outcome measure)|
|Experimental: Fractional carbon dioxide laser||
Procedure: Fractional carbon dioxide laser
SmartXide fractional carbon dioxide laser (DEKA, Florence, Italy). Parameters adjusted for: Power 20 watts, spacing 200 µsec, dwell time 300 µm, stacks 1.
Other Name: Ablative fractional laser resurfacing
|Contact: Vanessa G Hafez, MD||01001688434 ext email@example.com|
|Dermatology department - faculty of medicine- Cairo University||Not yet recruiting|
|Principal Investigator: Bakr M Elzawahry, MD|
|Principal Investigator: Vanessa G Hafez, MD|
|Principal Investigator: Aya Fahim, MBBCh|
|Study Chair:||Bakr M Elzawahry, MD||Cairo University|
|Principal Investigator:||Vanessa G Hafez, MD||Cairo University|
|Principal Investigator:||Aya Fahim, MBBCh||Cairo University|