Effectiveness of Aspirin in Compare With Heparin Plus Aspirin in Recurrent Pregnancy Loss Treatment
This study has been completed.
Information provided by (Responsible Party):
Yazd Medical University
First received: February 25, 2012
Last updated: March 1, 2012
Last verified: February 2012
This study evaluated the effect of anticoagulant treatment on the live-birth rate in women with a history of at least two continuous unexplained miscarriages or thrombophilia. It also compared two methods of treatment with aspirin and aspirin plus heparin.
||Observational Model: Case Control
Time Perspective: Retrospective
| Study Start Date:
recurrent pregnancy loss
|Ages Eligible for Study:
||19 Years to 35 Years
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
This project evaluated 520 women with unexplained recurrent miscarriage for four years. They had referred to recurrent abortion clinic of Yazd Reproductive sciences institute. Women with unexplained recurrent miscarriage included in this study
- unexplained recurrent miscarriage,
- women had previous venous or arterial thromboembolism or who were heterozygous or homozygous for mutations for FV Leiden G1691A, prothrombin gene G20210A (FII G20210A), and methyltetrahydrofolate reductase C677T (MTHFR C677T)
- abnormal karyotypes of both partners,
- uterine and cervical anatomical disorders on pelvic ultrasonography or hysteroscopy,
- abnormal ovaries and abnormal endocrine tests.
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Please refer to this study by its ClinicalTrials.gov identifier: NCT01542411
|Research and Clinical Centre for Infertility
|Yazd, Iran, Islamic Republic of |
Yazd Medical University
||Tahere Jahaninejad, MSC
||Yazd Shahid Sadoughi Medical Sciences University and Health Services, Yazd, Iran
No publications provided
||Yazd Medical University
History of Changes
|Other Study ID Numbers:
|Study First Received:
||February 25, 2012
||March 1, 2012
||Iran: Ethics Committee
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on August 20, 2014
Anti-Inflammatory Agents, Non-Steroidal
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Fibrin Modulating Agents
Molecular Mechanisms of Pharmacological Action
Platelet Aggregation Inhibitors
Central Nervous System Agents