Gestational Diabetes Diagnostic Methods (GD2M)

This is a pilot feasibility study of 40 pregnant women between 24-28 weeks gestation to test the investigators recruitment, enrollment and randomization procedures in preparation to conduct a larger randomized control trial to compare diagnostic methods for gestational diabetes. Forty women 18 years of age or older will be recruited at 20-24 weeks pregnancy from the ob/gyn outpatient practices at Magee-Women's hospital (MWH). Eligible women will return to MWH main lab between 24-28 weeks gestation for the routine 1 hour 50gm glucose challenge test. Women with blood glucose values less than 200 will return within 1 week and receive either the fasting 2 hour 75 gm oral glucose tolerance test or the 3 hour 100 gm OGGT. Gestational diabetes will be determined for the 2 hour 75 gm OGGT based on the 2011 ADA guidelines and the 3 hour 100 gm OGGT based on the Carpenter and Coustan criteria. Patients and their providers will be informed of the diagnosis of gestational diabetes, but they will be blinded to the criteria used to make the diagnosis as well as the specific results of glucose tolerance testing. Chart reviews will be conducted to assess for perinatal maternal and infant health factors (e.g.pregnancy weight, gestational weight gain, co morbidities) as well as for data on perinatal outcomes related to GDM such as macrosomia, c-sections, birth trauma. Two brief self-administered questionnaire will assess participant's views on screening for gestational diabetes and assess participants experience with and solicit feedback on the study procedures. At the end of this pilot study will have experience with the investigators recruitment, retention and randomization procedures and have made the necessary protocol revisions. This feasibility study if successful will provide the preliminary data and feasibility justification needed to conduct a larger randomized control trial to compare the effectiveness of two diagnostic methods for gestational diabetes.