Internet-delivered Psychodynamic Therapy for Depression and Anxiety Disorders (ATLAS)

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Gerhard Andersson, Linkoeping University
ClinicalTrials.gov Identifier:
NCT01532219
First received: February 9, 2012
Last updated: April 23, 2013
Last verified: April 2013
  Purpose

The overall aim of this study is to develop and test a psychodynamic Internet-delivered psychological treatment for patients with major depression and/or anxiety disorders and compare its efficacy to an active control group.


Condition Intervention
Depression
Anxiety
Behavioral: Internet-delivered Psychodynamic Treatment
Behavioral: Internet-delivered structured support

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Internet-delivered Psychodynamic Therapy for Depression and Anxiety Disorders: A Randomized Controlled Trial

Resource links provided by NLM:


Further study details as provided by Linkoeping University:

Primary Outcome Measures:
  • 9-item Patient Health Questionnaire Depression Scale (PHQ-9) [ Time Frame: Two weeks before the treatment starts ] [ Designated as safety issue: No ]
  • 7-item Patient Health Questionnaire Generalized Anxiety Disorder Scale (GAD-7) [ Time Frame: Two weeks before the treatment starts ] [ Designated as safety issue: No ]
  • 9-item Patient Health Questionnaire Depression Scale (PHQ-9) [ Time Frame: At treatment start (0 weeks) ] [ Designated as safety issue: No ]
  • 7-item Patient Health Questionnaire Generalized Anxiety Disorder Scale (GAD-7) [ Time Frame: At treatment start (0 weeks) ] [ Designated as safety issue: No ]
  • 9-item Patient Health Questionnaire Depression Scale (PHQ-9) [ Time Frame: At treatment termination (10 weeks) ] [ Designated as safety issue: No ]
  • 7-item Patient Health Questionnaire Generalized Anxiety Disorder Scale (GAD-7) [ Time Frame: At treatment termination (10 weeks) ] [ Designated as safety issue: No ]
  • 9-item Patient Health Questionnaire Depression Scale (PHQ-9) [ Time Frame: At treatment follow-up (7 months) ] [ Designated as safety issue: No ]
  • 7-item Patient Health Questionnaire Generalized Anxiety Disorder Scale (GAD-7) [ Time Frame: At treatment follow-up (7 months) ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Emotional Processing Scale (EPS-25) [ Time Frame: Two weeks before the treatment starts ] [ Designated as safety issue: No ]
  • Emotional Processing Scale (EPS-25) [ Time Frame: At treatment start (0 weeks) ] [ Designated as safety issue: No ]
  • Emotional Processing Scale (EPS-25) [ Time Frame: At treatment termination (10 weeks) ] [ Designated as safety issue: No ]
  • Five Facets of Mindfulness Questionnaire (FFMQ) [ Time Frame: Two weeks before the treatment starts ] [ Designated as safety issue: No ]
  • Five Facets of Mindfulness Questionnaire (FFMQ) [ Time Frame: At treatment start (0 weeks) ] [ Designated as safety issue: No ]
  • Five Facets of Mindfulness Questionnaire (FFMQ) [ Time Frame: At treatment termination (10 weeks) ] [ Designated as safety issue: No ]
  • Emotional Processing Scale (EPS-25) [ Time Frame: At treatment follow-up (7 months) ] [ Designated as safety issue: No ]
  • Five Facets of Mindfulness Questionnaire (FFMQ) [ Time Frame: At treatment follow-up (7 months) ] [ Designated as safety issue: No ]

Enrollment: 100
Study Start Date: February 2012
Study Completion Date: December 2012
Primary Completion Date: December 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Internet-delivered Psychodynamic Treatment
Participants in the experimental condition will receive 8 text-modules delivered as guided self-help, via the Internet. The intervention lasts for 10 weeks and includes weekly contacts with a therapist via a secure online environment similar to e-mail. The treatment is a short-term psychodynamic treatment psychodynamic treatment.
Behavioral: Internet-delivered Psychodynamic Treatment
Ten weeks of guided self-help + therapist contact, via the Internet.
Active Comparator: Internet-delivered structured support
Participants in the active control condition will receive a structured support treatment via the Internet. The intervention lasts for 10 weeks and includes weekly contacts with a therapist via a secure online environment similar to e-mail.
Behavioral: Internet-delivered structured support
Ten weeks of therapist contact, via the Internet.

  Eligibility

Ages Eligible for Study:   18 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Clinical diagnosis of Major Depressive Disorder, Panic Disorder, Social Anxiety Disorder, Generalized Anxiety disorder, Depressive Disorder NOS or Anxiety Disorder NOS
  • 10 or higher on the PHQ-9 or on the GAD-7 at pre-treatment

Exclusion Criteria:

  • Primary diagnosis of Obsessive Compulsive Disorder or Post-traumatic Stress Disorder
  • Severe psychiatric condition (e.g. psychosis or bipolar disorder)
  • Alcohol abuse (more than 16 on the AUDIT)
  • Suicidal (measured in diagnostic interview)
  • Changed medication during the last three months
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01532219

Locations
Sweden
Linköping University, Department of Behavioral Sciences and Learning
Linköping, Sweden, 58183
Sponsors and Collaborators
Linkoeping University
  More Information

No publications provided

Responsible Party: Gerhard Andersson, Professor of Clinical Psychology, Linkoeping University
ClinicalTrials.gov Identifier: NCT01532219     History of Changes
Other Study ID Numbers: GA-DEPANX2012-APT
Study First Received: February 9, 2012
Last Updated: April 23, 2013
Health Authority: Sweden: Regional Ethical Review Board

Additional relevant MeSH terms:
Anxiety Disorders
Depression
Depressive Disorder
Mental Disorders
Behavioral Symptoms
Mood Disorders

ClinicalTrials.gov processed this record on April 17, 2014