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Trial record 10 of 3740 for:    "Lung Diseases, Obstructive"
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Is the Short Physical Performance Battery a Useful Outcome Measure in Chronic Obstructive Pulmonary Disease

This study is currently recruiting participants.
Verified January 2012 by Royal Brompton & Harefield NHS Foundation Trust
Sponsor:
Collaborator:
Medical Research Council
Information provided by (Responsible Party):
Royal Brompton & Harefield NHS Foundation Trust
ClinicalTrials.gov Identifier:
NCT01515709
First received: January 10, 2012
Last updated: January 18, 2012
Last verified: January 2012
History of Changes
  Purpose

Patients with Chronic Obstructive Lung Disease (COPD) often develop muscle problems, particularly in their legs which makes them more limited in what they can do. The Short Physical Performance Battery (SPPB) is a simple test of standing balance, usual walking speed and ability to stand from a chair. The SPPB may be a useful measure to predict leg function.

This study aims to evaluate whether the SPPB is comparable with current exercise tests used in COPD patients, and whether it is useful in predicting disability, death and health resource usage over time.


Condition
Pulmonary Disease, Chronic Obstructive
Lung Diseases, Obstructive
Pulmonary Emphysema
Bronchitis, Chronic
Lung Diseases
Disease Progression

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Is the Short Physical Performance Battery a Useful Outcome Measure in Patients With Chronic Obstructive Pulmonary Disease ?

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Royal Brompton & Harefield NHS Foundation Trust:

Primary Outcome Measures:
  • Mortality rate [ Time Frame: 36 months ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Hospitalisation rate [ Time Frame: 36 months ] [ Designated as safety issue: No ]
  • Healthcare resource usage [ Time Frame: 36 months ] [ Designated as safety issue: No ]

Estimated Enrollment: 400
Study Start Date: April 2011
Estimated Study Completion Date: December 2015
Estimated Primary Completion Date: December 2012 (Final data collection date for primary outcome measure)
Groups/Cohorts
Chronic Obstructive Pulmonary Disease
Patients with a diagnosis of COPD

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Any patient with a diagnosis of COPD.

Criteria

Inclusion Criteria:

  • Diagnosis of COPD

Exclusion Criteria:

  • Any patient in whom mobility and lower limb function have been significantly affected by a neuromuscular cause (eg. motor neurone disease), severe peripheral vascular disease or amputation
  • Any patient whom is deemed unsafe to exercise
  • Patients unable to complete the SPPB, walking tests and leg strength assessments.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01515709

Contacts
Contact: Samantha SC Kon, BSc MRCP 01895 823 737 ext 5021 lungresearch@rbht.nhs.uk
Contact: Jane L Canavan, PhD 01895 823 737 ext 5021 lungresearch@rbht.nhs.uk

Locations
United Kingdom
Harefield Hospital Recruiting
Harefield, United Kingdom, UB9 6JH
Contact: Samantha SC Kon, BSc MRCP     01895 823 737 ext 5021     lungresearch@rbht.nhs.uk    
Contact: Jane L Canavan, PhD     01895 823 737 ext 5021     lungresearch@rbht.nhs.uk    
Sponsors and Collaborators
Royal Brompton & Harefield NHS Foundation Trust
Medical Research Council
Investigators
Principal Investigator: William DC Man, MRCP PhD NIHR Respiratory Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust
  More Information

Publications:

Responsible Party: Royal Brompton & Harefield NHS Foundation Trust
ClinicalTrials.gov Identifier: NCT01515709     History of Changes
Other Study ID Numbers: 2011LF001H
Study First Received: January 10, 2012
Last Updated: January 18, 2012
Health Authority: United Kingdom: Research Ethics Committee
United Kingdom: National Institute for Health Research
United Kingdom: National Health Service

Keywords provided by Royal Brompton & Harefield NHS Foundation Trust:
Cohort Studies
Longitudinal Studies

Additional relevant MeSH terms:
Lung Diseases, Obstructive
Bronchitis
Bronchitis, Chronic
Chronic Disease
Emphysema
Pulmonary Emphysema
Lung Diseases
Respiration Disorders
 Pulmonary Disease, Chronic Obstructive
Disease Progression
Bronchial Diseases
Respiratory Tract Diseases
Respiratory Tract Infections
Disease Attributes
Pathologic Processes

ClinicalTrials.gov processed this record on June 13, 2013