Quantitative EEG Assessment of Cue-Induced Changes in Brain Activity in Alcohol Use Disorders
Exposure to alcohol related cues, such as the sight of alcoholic drinks, may induce craving for alcohol in drinkers. In this study, the effects of exposure to (1) the pictures of alcoholic drinks and (2) the imagining of a scene related to drinking on activity in the frontal region of the brain in heavy social drinkers will be determined. This study is being conducted to develop the methods needed to allow for the detection of cue-induced changes in drinkers using the EEG. The objective of this pilot study is to establish procedures for detecting alcohol-related cue-elicited changes in EEG activity in heavy drinkers.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Quantitative EEG Assessment of Cue-Induced Changes in Brain Activity in Alcohol Use Disorders|
- FFT power of five frequency bands [ Designated as safety issue: No ]This study will look at FFT power of five frequency bands. Relative power will be determined by finding absolute power for the range of frequencies (0,1 to 100Hz). Relative power will then be found for each electrode. The Investigator's will examine change over time for relative power for each electrode in the different cue condition and compare change of power using repeated measures analysis with time and condition as within subject factors. Craving values obtained under the different cue conditions will be analyzed using condition as the within-subject factor.
|Study Start Date:||January 2012|
|Estimated Study Completion Date:||January 2015|
|Estimated Primary Completion Date:||January 2014 (Final data collection date for primary outcome measure)|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01507909
|Contact: Ofra Sarid-Segal, MDfirstname.lastname@example.org|
|United States, Massachusetts|
|Boston University Medical Center||Recruiting|
|Boston, Massachusetts, United States, 02118|
|Contact: Ofra Sarid-Segal, MD 617-414-1990 email@example.com|
|Principal Investigator:||Ofra Sarid-Segal, MD||Boston University|