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Multi-joint Coordination Underlies Upright Balance Control in Elderly With Osteoporosis

This study is currently recruiting participants.
Verified June 2011 by National Taiwan University Hospital
Sponsor:
Information provided by (Responsible Party):
National Taiwan University Hospital
ClinicalTrials.gov Identifier:
NCT01504230
First received: January 3, 2012
Last updated: January 4, 2012
Last verified: June 2011
History of Changes
  Purpose

Osteoporosis is a prevalent health concern among older adults and is associated with an increased risk of falls that can cause fracture, injury and even mortality. Identifying the factors related to falls occur within this population is essential for the development of effective regimes for fall prevention. The long-term objectives of this work are to ascertain the mechanisms for effectively controlling balance in seniors with osteoporosis and to provide a basis for developing fall prevention programs. The entire body's center of mass (CoM) is a critical indicator for balance control and the coordination among joints and muscles to control the CoM is still unclear. The aim1 of this study is to develop biomechanical models that control the entire body's center of mass (CoM) during upright quiet stance in seniors with osteoporosis. The aim2 of this study is to identify the mechanism to control the entire body's CoM after receiving a balance perturbation in seniors with osteoporosis. The findings of this research can provide needed information regarding the processes of balance control in this vulnerable osteoporosis population, and has the potential to be applied to individuals with other neuromuscular and orthopedic deficits.


Condition
Osteoporosis

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Multi-joint Coordination Underlies Upright Balance Control in Elderly With Osteoporosis

Resource links provided by NLM:

MedlinePlus related topics: Osteoporosis
U.S. FDA Resources

Further study details as provided by National Taiwan University Hospital:

Estimated Enrollment: 80
Study Start Date: September 2011
  Eligibility

Ages Eligible for Study:   65 Years to 85 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population

community sample

Criteria

Inclusion Criteria:

  • for healthy older adults (OA)

    1. can stand for 5 minutes and walk for 6 minutes independently
    2. normal or corrected to normal vision
    3. an age between 65-85 years
    4. no osteoporosis (T-score above -2.5)

  • for osteoporosis participants (OP)

    1. can stand for 5 minutes and walk for 6 minutes independently
    2. normal or corrected to normal vision
    3. an age between 65-85 years
    4. no osteoporosis (T-score below -2.5)

Exclusion Criteria:

  1. pregnant women
  2. cancer diagnosis
  3. sensory-motor deficits
  4. the BMI is larger than 30 or smaller than 18
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01504230

Contacts
Contact: Wei-Li Hsu, PhD 886-2-33668127 wlhsu@ntu.edu.tw

Locations
Taiwan
School & Graduate Institute of Physical Therapy College of Medicine, National Taiwan University Recruiting
Taipei, Taiwan
Contact: Wei-Li Hsu, PT, Phd     886-2-33668127     wlhsu@ntu.edu.tw    
School & Graduate Institute of Physical Therapy College of Medicine, National Taiwan University Recruiting
Taipei, Taiwan
Contact: Wei-Li Hsu, PhD     886-2-33668127     wlhsu@ntu.edu.tw    
Sponsors and Collaborators
National Taiwan University Hospital
Investigators
Principal Investigator: Wei-Li Hsu, PhD National Taiwan University Hospital
  More Information

No publications provided

Responsible Party: National Taiwan University Hospital
ClinicalTrials.gov Identifier: NCT01504230     History of Changes
Other Study ID Numbers: 201104056RB
Study First Received: January 3, 2012
Last Updated: January 4, 2012
Health Authority: Taiwan: Department of Health

Keywords provided by National Taiwan University Hospital:
To ascertain the mechanisms for effectively controlling balance in seniors with osteoporosis and to provide a basis for developing fall prevention programs.
To develop biomechanical models that control the entire body's center of mass (CoM) during upright quiet stance in seniors with osteoporosis.
To identify the mechanism to control the entire body's CoM after receiving a balance perturbation in seniors with osteoporosis.

Additional relevant MeSH terms:
Osteoporosis
Bone Diseases, Metabolic
Bone Diseases
Musculoskeletal Diseases

ClinicalTrials.gov processed this record on May 16, 2013