The Immune System's Response to Young Women's Breast Cancer
This study plans to learn more about the immune system's response to breast cancer in young women.
Breast Cancer and Pregnancy
|Study Design:||Time Perspective: Retrospective|
|Official Title:||A Translational Study of the Interactions Between Prior Pregnancy and the Biologic Subtype of Breast Cancer in Defining the Cancer: Host Immunologic Interaction|
- Progression Free Survival [ Time Frame: Throughout study participation ] [ Designated as safety issue: No ]Prospective cohort study.
Biospecimen Retention: Samples With DNA
Tissue, Blood and urine may be collected from subjects who were recently diagnosed. Subjects who were diagnosed after treatment begins or has ended will only be eligible for tissue donation section of study
|Study Start Date:||July 2007|
|Estimated Study Completion Date:||July 2021|
|Estimated Primary Completion Date:||December 2020 (Final data collection date for primary outcome measure)|
The investigators will be looking at the level of immune suppression in different types of breast cancer. The investigators will use blood, urine, and tissue samples from patients with Pregnancy Associated Breast Cancer (PABC) versus non-PABC, as well as comparing different types of breast cancer. If tissue sampling permits, the investigators may use some of the breast cancer tissue to develop models for human cancer for drug targeting. Understanding the immune response and suppression in different types of cancer will help us understand mechanisms involved in breast cancer better and help the investigators in developing new treatment in the future.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01503190
|Contact: Tiffany Colvin, BS||720-848-0664||Tiffany.Colvin@ucdenver.edu|
|United States, Colorado|
|University of Colorado Denver||Recruiting|
|Aurora, Colorado, United States, 80045|
|Principal Investigator:||Virginia Borges, MD, MMSc||University of Colorado, Denver|