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Early Reassessment of Intravenous Antiinfective Therapy Due to "Antiinfective Reminders" (AIR Study)

This study is currently recruiting participants.
Verified July 2012 by University of Zurich
Sponsor:
Information provided by (Responsible Party):
University of Zurich
ClinicalTrials.gov Identifier:
NCT01499927
First received: November 15, 2011
Last updated: July 4, 2012
Last verified: July 2012
History of Changes
  Purpose

Switching from intravenous application of antiinfective agents to oral therapy is often performed late including high costs and risk of complications. This study will investigate the impact of displayed reminders in the electronic patient chart after 60h of intravenous therapy with an antiinfective agent.


Condition Intervention
Infection as Complication of Medical Care
 Other: electronic reminders

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Subject)
Primary Purpose: Health Services Research
Official Title: Early Reassessment of Intravenous Antiinfective Therapy Due to "Antiinfective Reminders" (AIR Study)

Further study details as provided by University of Zurich:

Primary Outcome Measures:
  • duration of intravenous antiinfective therapy until switching [ Time Frame: 1 year ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • costs (per year, per day and patient) [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  • defined daily doses (per 100 days) [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  • duration of hospitalization [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  • ratio of narrow to broad-spectrum antibiotics [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  • requests for consultations [ Time Frame: 1 year ] [ Designated as safety issue: No ]

Estimated Enrollment: 30000
Study Start Date: January 2012
Estimated Study Completion Date: December 2012
Estimated Primary Completion Date: December 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: electronic reminders
Behavioral: Early switching from intravenous to oral antiinfective agents due to electronic reminders
 Other: electronic reminders
Behavioral: Early switching from intravenous to oral antiinfective agents due to electronic reminders
Other Name: computerized decision support
No Intervention: no electronic reminders
Behavioral: Early switching from intravenous to oral antiinfective agents without computerized decision support

Detailed Description:

Switching from intravenous application of antiinfective agents to oral therapy is often performed late including high costs, risk of complications as well as higher workload on nursing. This study will investigate the impact of displayed reminders in the electronic patient chart after 60h of intravenous therapy with an antiinfective agent.

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion criteria:

  • all in-patients in treatment with an intravenous antiinfective for >60h,
  • hospitalized in a ward with computerized physician order entry (cpoe)

Exclusion criteria:

  • outpatients,
  • ward without cpoe,
  • no intravenous antiinfective treatment
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01499927

Contacts
Contact: Patrick Beeler, MD +41 44 255 10 95 patrick.beeler@usz.ch
Contact: Juerg Blaser, Professor +41 44 255 36 18 juerg.blaser@usz.ch

Locations
Switzerland
University Hospital Zurich, Center for Clinical Research Recruiting
Zurich, ZH, Switzerland, 8091
Sponsors and Collaborators
University of Zurich
Investigators
Principal Investigator: Juerg Blaser, Professor University Hospital Zurich, Center for Clinical Research
  More Information

No publications provided

Responsible Party: University of Zurich
ClinicalTrials.gov Identifier: NCT01499927     History of Changes
Other Study ID Numbers: FZMI-KEK-ZH-Nr. 2010-0457
Study First Received: November 15, 2011
Last Updated: July 4, 2012
Health Authority: Switzerland: Ethikkommission

Keywords provided by University of Zurich:
Early reassessment of intravenous antiinfective therapy

Additional relevant MeSH terms:
Anti-Infective Agents
Therapeutic Uses
Pharmacologic Actions

ClinicalTrials.gov processed this record on May 16, 2013