Comparison of Nasal CPAP and Nasal SIMV in Transient Tachypnea of Newborn

This study is currently recruiting participants.
Verified December 2011 by Zekai Tahir Burak Maternity and Teaching Hospital
Sponsor:
Information provided by (Responsible Party):
Gamze Demirel, Zekai Tahir Burak Maternity and Teaching Hospital
ClinicalTrials.gov Identifier:
NCT01499238
First received: December 14, 2011
Last updated: December 21, 2011
Last verified: December 2011
  Purpose

The investigators aimed to compare the efficacy of nasal SIMV and nasal CPAP in patients with wet lung.


Condition Intervention Phase
Transient Tachypnea of Newborn
Device: Nasal SIMV
Device: nasal CPAP
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Comparison of Nasal CPAP and Nasal SIMV in Transient Tachypnea of Newborn

Resource links provided by NLM:


Further study details as provided by Zekai Tahir Burak Maternity and Teaching Hospital:

Primary Outcome Measures:
  • efficacy of nasal SIMV and nasal CPAP in infants with wet lung who are >35 weeks gestational age [ Time Frame: 3 months ] [ Designated as safety issue: Yes ]

Secondary Outcome Measures:
  • Complications of respiratory support, respiratory insufficiency [ Time Frame: 3 months ] [ Designated as safety issue: Yes ]
    pneumothorax


Estimated Enrollment: 40
Study Start Date: December 2011
Estimated Study Completion Date: March 2012
Estimated Primary Completion Date: February 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: nasal SIMV
rate: 30-50/min, PIP: 16, PEEP: 4-6, fİO2: 40%
Device: Nasal SIMV
rate: 30-50/min, PIP: 16-20, PEEP: 4-6, FİO2: 40%
Other Name: nasal SIMV, SLE 5000
Active Comparator: nasal CPAP
PEEP: 4-6 mmHg, Fio2: 40%
Device: nasal CPAP
PEEP: 4-6 mmHg, FİO2: 40%
Other Name: NASAL CPAP, SLE 5000

Detailed Description:

We aimed to compare two types of ventilatory support in cases of transient tachypnea of newborn who are >35 gestational week.

  Eligibility

Ages Eligible for Study:   up to 3 Days
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • >35 gestational week
  • wetlung

Exclusion Criteria:

  • major congenital anomalies
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01499238

Contacts
Contact: Gamze Demirel, MD kgamze@hotmail.com

Locations
Turkey
Zekai Tahir Burak Maternity Teaching Hospital, Division of Neonatology Recruiting
Ankara, Turkey
Contact: Gamze Demirel, MD         kgamze@hotmail.com    
Principal Investigator: Gamze Demirel, MD            
Zekai Tahir Burak Maternity Teaching Hospital Recruiting
Ankara, Turkey
Contact: Gamze Demirel, MD         kgamze@hotmail.com    
Sponsors and Collaborators
Zekai Tahir Burak Maternity and Teaching Hospital
Investigators
Principal Investigator: Gamze Demirel, MD Zekai Tahir Burak Maternity Teaching Hospital
  More Information

No publications provided

Responsible Party: Gamze Demirel, Zekai Tahir Burak Maternity Teaching Hospital, Zekai Tahir Burak Maternity and Teaching Hospital
ClinicalTrials.gov Identifier: NCT01499238     History of Changes
Other Study ID Numbers: 4
Study First Received: December 14, 2011
Last Updated: December 21, 2011
Health Authority: Turkey: Ethics Committee

Keywords provided by Zekai Tahir Burak Maternity and Teaching Hospital:
Efficacy
safety
nasal SIMV
nasal CPAP
infants who are >35 gestational week with wet lung

ClinicalTrials.gov processed this record on May 19, 2013