Hypoparathyroidism in Denmark (HypoPT)

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
University of Aarhus
ClinicalTrials.gov Identifier:
NCT01498341
First received: December 20, 2011
Last updated: June 30, 2014
Last verified: January 2013
  Purpose

The purpose of this study is to identify the number of persons in Denmark with the diagnose hypoparathyroidism, autosomal dominant hypocalcaemia or pseudohypoparathyroidism. Also the investigators want to identify the causes and symptoms of these patients and their prognosis.


Condition
Hypoparathyroidism

Study Type: Observational
Official Title: Hypoparathyroidism, Autosomal Dominant Hypocalcaemia and Pseudohypoparathyroidism in Denmark - Epidemiology, Causes, Symptoms and Prognoses

Resource links provided by NLM:


Further study details as provided by University of Aarhus:

Primary Outcome Measures:
  • Frequency of hypoparathyroidism, pseudohypoparathyroidism and autosomal dominant hypocalcaemia and its consequences [ Time Frame: One year ] [ Designated as safety issue: No ]

    The frequency of hypoparathyroidism, pseudohypoparathyroidism and autosomal dominant hypocalcaemia. The frequence is estimated via the National Danish Health Register.

    The prevalence of kidney-, cardiovascular- and neuropsychiatric disease, fertility, hospitalization required hypo- or hypercalcaemia, overall number of hospitalizations and mortality.



Biospecimen Retention:   None Retained

2 designs: Case-finding; Case-control


Enrollment: 1000
Study Start Date: August 2011
Study Completion Date: May 2012
Primary Completion Date: May 2012 (Final data collection date for primary outcome measure)
  Show Detailed Description

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

The study population are persons with hypoparathyroidism, automalt dominant hypocalcaemia and pseudohypoparathyroidism.

The population is selected via the National Danish Health Registre and the Danish Medical Registre

Criteria

Inclusion Criteria for the case-control-study:

  • Idiopathic hypoparathyroidism
  • Pseudohypoparathyroidism
  • Autosomal dominant hypocalcaemia

Exclusion Criteria for the case-control-study:

  • Chronic kidney insufficience (creatinine above 200 umol/l)
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01498341

Locations
Denmark
Department of Internal Medicine and Endocrinology, Aarhus University Hospital, Tage-Hansens Gade
Aarhus, Region Midt, Denmark, 8000
Sponsors and Collaborators
University of Aarhus
Investigators
Principal Investigator: Lars Rejnmark, DmSci, PhD Aarhus University Hospital
  More Information

No publications provided

Responsible Party: University of Aarhus
ClinicalTrials.gov Identifier: NCT01498341     History of Changes
Other Study ID Numbers: M-20110074
Study First Received: December 20, 2011
Last Updated: June 30, 2014
Health Authority: Denmark: Danish Dataprotection Agency
Denmark: The Regional Committee on Biomedical Research Ethics

Keywords provided by University of Aarhus:
Hypoparathyroidism
Epidemiology
Prognosis
Symptoms

Additional relevant MeSH terms:
Hypoparathyroidism
Parathyroid Diseases
Endocrine System Diseases

ClinicalTrials.gov processed this record on October 01, 2014