The Changes of CD4+T Lymphocyte Subsets in Septic Patients
The purpose of this study is to explore the value of CD4+T lymphocyte subsets in cell immunity in the patients with sepsis.There are immunoparalysis in septic patients,the important player is the change of CD4+T lymphocyte,this immunoparalysis state contribute to the illness progress and outcome. Comprehend the change regularity of septic patients' cell immunity can guide fiter and correcter treatment.
SIRS(Systemic Inflammatory Response Syndrome)
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||The Role of CD4+T Lymphocyte Subsets in Cell Immunity in Patients With Sepsis|
|Study Start Date:||August 2011|
|Estimated Study Completion Date:||March 2012|
|Estimated Primary Completion Date:||March 2012 (Final data collection date for primary outcome measure)|
(1) temperature > 38oC or < 36oC; (2) pulse rate > 90 beats/min; (3) ventilation rate > 20 breaths/min or hyperventilation with a partial pressure of arterial carbon dioxide (PaCO2) < 32 mmHg; (4) white blood cell (WBC) count >1 2,000μL-1 or < 4000 μL-1 , or > 10% immature cells.
SIRS + infection
not SIRS and have no infection
|Chinese PLA General Hospital|
|Beijing, Beijing, China, 100853|
|Study Director:||Xie Li Xin, Doctor||Department Of Respiratory Diseases, Chinese PLA General Hospital|