Biomarkers in Samples From Younger Patients With Wilms Tumor
Recruitment status was Active, not recruiting
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. It may also help doctors predict how patients respond to treatment.
PURPOSE: This research study is studying biomarkers in tissue samples from younger patients with Wilms tumor.
Genetic: microarray analysis
Other: laboratory biomarker analysis
Other: medical chart review
|Official Title:||Relationships Between Tumor-Associated Macrophages and Clinicopathological Factors in Wilms Tumor|
- Relationship of tumor-associated macrophages and prognosis [ Designated as safety issue: No ]
|Study Start Date:||December 2011|
|Estimated Primary Completion Date:||February 2012 (Final data collection date for primary outcome measure)|
- To determine whether recruitment of tumor-associated macrophages is related to clinicopathological factors in Wilms tumor (tumor stage, presence of vascular invasion, tumor progression, and survival).
OUTLINE: Paraffin-embedded specimens are analyzed for macrophage markers. Results of each sample is then compared with patient's tumor stage, presence of vascular invasion, tumor progression, and survival.
|Principal Investigator:||Jessica Kandel, MD||Morgan Stanley Children's Hospital of New York-Presbyterian|