Differences in Nerve Fiber Layer Between Patients With Normal- and High-Pressure-Glaucoma
The purpose of the study is to prove if there is any difference in the nerve fiber layer between patients with normal- and high-tension-glaucoma with similar structural optic nerve head parameters.
Normal Tension Glaucoma
High Tension Glaucoma
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Differences in Nerve Fiber Layer Between Patients With Normal- and High-Pressure-Glaucoma With Similar Structural Optic Nerve Damage|
- RNFL in different segments [ Time Frame: up to 9 Months ] [ Designated as safety issue: No ]RNFL in upper, lower, temporal and nasal segments
|Study Start Date:||March 2011|
|Study Completion Date:||November 2011|
|Primary Completion Date:||November 2011 (Final data collection date for primary outcome measure)|
subjects with IOP>22 mmHg without eyedrops and signs of glaucomatous optic nerve damage
subjects with IOP<22 mmHg without eyedrops and signs of glaucomatous optic nerve damage
It is till now not definitely clear whether normal- and high-tension glaucoma are different forms of the same disease and whether they have similar pathogenetic mechanisms. Spectral domain optical coherence tomography (SD-OCT) is supposed to objectively evaluate retinal nerve fiber layer (RNFL) thickness. The investigators propose a study to compare the RNFL in patients with normal- and high-tension-glaucoma. In order to exclude other possible differences,which could influence the results, only patients with similar structural optic nerve head damage in both groups will be compared.