Trial record 1 of 4 for:    "Alveolitis extrinsic allergic"
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Wind Instruments' Fungal Contamination

This study has been completed.
Information provided by (Responsible Party):
Flora METZGER, Centre Hospitalier Universitaire de Besancon Identifier:
First received: December 6, 2011
Last updated: December 8, 2011
Last verified: December 2011

On the basis of 2 cases of immunologically-induced lung disease in 2 saxophonists, the investigators supposed that wind reed instruments could be contaminated with molds. The investigators led a study on 40 musicians playing a wind reed instrument to analyze instruments' fungal contamination and its immunological and clinical consequences for musicians.

Condition Intervention
Immunologically-induced Lung Disease
Hypersensitivity Pneumonitis
Biological: blood sample

Study Type: Interventional
Study Design: Primary Purpose: Diagnostic
Official Title: Study of Wind Reed Instruments' Fungal Contamination and Its Immunological and Clinical Consequences for Musicians.

Resource links provided by NLM:

Further study details as provided by Centre Hospitalier Universitaire de Besancon:

Study Start Date: May 2007
Study Completion Date: October 2007
Primary Completion Date: June 2007 (Final data collection date for primary outcome measure)
Intervention Details:
    Biological: blood sample
    blood sample in each musician to search for specific antibodies against molds isolated from instruments

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • must be 18 year old or more
  • must play a wind reed instrument (saxophone, clarinet, bassoon or oboe) one hour per week or more

Exclusion Criteria:

  • refuse to sign consent
  Contacts and Locations
Please refer to this study by its identifier: NCT01487850

Centre Hospitalier Universitaire Saint Jacques
Besancon, Franche Comté, France, 25000
Sponsors and Collaborators
Centre Hospitalier Universitaire de Besancon
  More Information

Responsible Party: Flora METZGER, Medical Doctor, Lung specialist, Principal Investigator, Centre Hospitalier Universitaire de Besancon Identifier: NCT01487850     History of Changes
Other Study ID Numbers: P/2007/55
Study First Received: December 6, 2011
Last Updated: December 8, 2011
Health Authority: France: Délégation à la Recherche Clinique et à l'Innovation

Keywords provided by Centre Hospitalier Universitaire de Besancon:
wind instruments
hypersensitivity pneumonitis
fungal contamination of wind instruments
specific antibodies against molds in musicians' sera

Additional relevant MeSH terms:
Alveolitis, Extrinsic Allergic
Lung Diseases
Lung Diseases, Interstitial
Respiratory Tract Diseases
Respiratory Hypersensitivity
Hypersensitivity, Immediate
Immune System Diseases
Respiratory Tract Infections processed this record on April 16, 2014