A Pilot Study to Evaluate Multi-Spectral Imaging and Laser Speckle Imaging During Vascular Occlusion
The purpose of this research is to evaluate and validate the performance of non-invasive imaging modalities for assessment of skin. A pressure cuff occlusion will be used to stimulate blood flow dynamic that these instruments are designed to sense. The researcher currently plan to assess only basic feasibility of the imaging instruments.
|Study Design:||Observational Model: Case-Only
Time Perspective: Cross-Sectional
|Official Title:||A Pilot Study to Evaluate Multi-Spectral Imaging and Laser Speckle Imaging During Vascular Occlusion|
- Skin blood flow [ Time Frame: 4 weeks ] [ Designated as safety issue: No ]
|Study Start Date:||November 2011|
|Estimated Study Completion Date:||November 2018|
|Estimated Primary Completion Date:||November 2018 (Final data collection date for primary outcome measure)|
Multi-Spectral & Laser Speckle Imaging
Device: Multi-Spectral & Laser Speckle Imaging
Changes in skin tissue and blood flow.
Other Name: Multi-Spectral & Laser Speckle Imaging
The primary reason for including pressure cuff occlusion in this protocol is to test the performance of Multi-Spectral Imaging and Laser Speckle Imaging can measure in the full range of vascular conditions ranging from ischemic (under-perfused or unsaturated) to hyperemic (over-perfused and over-saturated).
- .Modulated Imaging a non-contact optical imaging technology can detect the concentration of total hemoglobin, deoxygenated and oxygenated hemoglobin in absolute amounts in units of millimoles / unit volume of tissue measured.
- . Laser Speckle Imaging a non-contact optical imaging technology consists of a coherent light source, camera, and image acquisition system. This image device can measure and compare relative flow in vasculature at varied time points.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01484730
|United States, California|
|Beckman Laser Institute, UCI|
|Irvine, California, United States, 92612|
|Principal Investigator:||Anthony Durkin, PhD||Beckman Laser Institute, UCI|