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Treatments of Acquired Apraxia of Speech

This study is currently recruiting participants.
Verified March 2013 by Department of Veterans Affairs
Sponsor:
Information provided by (Responsible Party):
Department of Veterans Affairs
ClinicalTrials.gov Identifier:
NCT01483807
First received: April 15, 2011
Last updated: March 1, 2013
Last verified: March 2013
History of Changes
  Purpose

This study is designed to examine the effects of speech therapy on ability to produce speech sounds in persons with acquired apraxia of speech.


Condition Intervention Phase
Blocked
Randomized
 Behavioral: Sound Production Treatment
 Phase 1

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Treatments of Acquired Apraxia of Speech

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Department of Veterans Affairs:

Primary Outcome Measures:
  • speech production [ Time Frame: Pre treatment (2-3 week period preceding the start of treatment) , Interim treatment (after 20 treatment session - approximately 7 weeks after the start of treatment), and Post treatment (after another 20 treatment sessions - approximately 15 weeks) ] [ Designated as safety issue: No ]
    accuracy of articulation


Estimated Enrollment: 24
Study Start Date: August 2011
Estimated Study Completion Date: June 2015
Estimated Primary Completion Date: January 2015 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Arm 1
two groups will receive treatment
 Behavioral: Sound Production Treatment
A treatment for acquired apraxia of speech. Combines therapist modeling, simultaneous production, articulatory instruction, feedback and repeated practice

Detailed Description:

This study is designed to investigate the effects of Sound Production Treatment (SPT; a treatment for acquired apraxia of speech) on sound production accuracy in persons with chronic apraxia of speech (AOS). Organization of practice (blocked practice or randomized practice) will be manipulated in an effort to determine the most efficacious application of SPT. A combination of group and single-subject experimental designs will be completed with 24 speakers with AOS (2 groups of 12 participants).

  Eligibility

Ages Eligible for Study:   21 Years to 85 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Must have acquired apraxia of speech that occurred following a stroke or other brain injury.
  • Must be at least 6 months post-onset of brain injury.
  • May have aphasia.

Exclusion Criteria:

  • History of drug or alcohol abuse.
  • History of mental illness.
  • Neurological condition other than that which resulted in apraxia of speech.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01483807

Contacts
Contact: Julie L Wambaugh, PhD (801) 582-1565 Julie.Wambaugh@va.gov
Contact: Christina Nessler, MS (801) 582-1565 ext 5379 christina.nessler@va.gov

Locations
United States, Utah
VA Salt Lake City Health Care System, Salt Lake City Recruiting
Salt Lake City, Utah, United States, 84148
Contact: Julie L Wambaugh, PhD     801-582-1565     Julie.Wambaugh@va.gov    
Principal Investigator: Julie L. Wambaugh, PhD            
Sponsors and Collaborators
Department of Veterans Affairs
Investigators
Principal Investigator: Julie L. Wambaugh, PhD VA Salt Lake City Health Care System, Salt Lake City
  More Information

No publications provided

Responsible Party: Department of Veterans Affairs
ClinicalTrials.gov Identifier: NCT01483807     History of Changes
Other Study ID Numbers: C7419-R
Study First Received: April 15, 2011
Last Updated: March 1, 2013
Health Authority: United States: Federal Government

Keywords provided by Department of Veterans Affairs:
speech
speech therapy
apraxia of speech

Additional relevant MeSH terms:
Apraxias
Psychomotor Disorders
Neurobehavioral Manifestations
 Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms

ClinicalTrials.gov processed this record on June 18, 2013