Vascular Occlusion in Patients With Osteoarthritis

This study is currently recruiting participants. (see Contacts and Locations)
Verified February 2014 by University of Sao Paulo
Sponsor:
Information provided by (Responsible Party):
Bruno Gualano, University of Sao Paulo
ClinicalTrials.gov Identifier:
NCT01483131
First received: November 29, 2011
Last updated: February 27, 2014
Last verified: February 2014
  Purpose

Resistance exercise plus vascular occlusion may induce greater improvements in strength and muscle mass than resistance training alone. The investigators speculate this training strategy could be beneficial in patients with osteoarthritis.


Condition Intervention
Osteoarthritis
Other: Exercise training
Other: Resistance training with vascular occlusion

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Effects of Strength Training Associated With Vascular Occlusion in Patients With Knee Osteoarthritis

Resource links provided by NLM:


Further study details as provided by University of Sao Paulo:

Primary Outcome Measures:
  • muscle strength [ Time Frame: 12 weeks ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Quality of Life [ Time Frame: 12 weeks ] [ Designated as safety issue: No ]

Estimated Enrollment: 45
Study Start Date: November 2011
Estimated Study Completion Date: December 2014
Primary Completion Date: November 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Low intensity resistance training Other: Exercise training
12 weeks of resistance training twice a week.
Experimental: High intensity resistance training Other: Exercise training
12 weeks of resistance training twice a week.
Experimental: Low intensity resistance training with vascular occlusion Other: Resistance training with vascular occlusion
12 weeks of resistance training with vascular occlusion twice a week

  Eligibility

Ages Eligible for Study:   50 Years to 65 Years
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Postmenopausal women
  • BMI <39
  • Knee Ostearthritis type II and III
  • VAS (visual analogue scale) between 2 and 8

Exclusion Criteria:

  • Hip osteoarthritis
  • Use of NSAID
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01483131

Contacts
Contact: Rodrigo Ferraz, Msc 55 11 8122 1203 ferraz@email.com

Locations
Brazil
University of Sao Paulo -School of Medicine - Clinical Hospital Recruiting
Sao Paulo, Brazil, 05403 010
Contact: Rodrigo Ferraz, Msc    55 11 8122 1203    ferraz@email.com   
Principal Investigator: Hamilton Roschel, PhD         
Principal Investigator: Ana Lucia Sá Pinto, PhD         
Sub-Investigator: Bruno Gualano, PhD         
Sponsors and Collaborators
University of Sao Paulo
  More Information

No publications provided

Responsible Party: Bruno Gualano, Professor, University of Sao Paulo
ClinicalTrials.gov Identifier: NCT01483131     History of Changes
Other Study ID Numbers: vascular occlusion and OA
Study First Received: November 29, 2011
Last Updated: February 27, 2014
Health Authority: Brazil: National Committee of Ethics in Research

Additional relevant MeSH terms:
Osteoarthritis
Osteoarthritis, Knee
Arthritis
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases

ClinicalTrials.gov processed this record on August 28, 2014