How Has Glaucoma Affected Your Quality of Life?
Hypothesis 1: Self-reported health-related quality of life decreases as vision impairment worsens in subjects with glaucoma.
Hypothesis 2: Changes in health-related quality of life are associated with changes in clinical measures of vision and performance-based measures of visual function.
Quality of Life
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||A Prospective, Longitudinal, Observational Cohort Study Examining How Glaucoma Affects Quality of Life and Visual Function Over a 4-Year Period|
- Quality of Life [ Time Frame: 1, 2, 3, 4, and 5 years ] [ Designated as safety issue: No ]Quality of life questionnaire
- Clinical Findings [ Time Frame: 1, 2, 3, 4, and 5 years ] [ Designated as safety issue: No ]Intraocular pressure
- Quality of Life [ Time Frame: 1, 2, 3, 4, and 5 years ] [ Designated as safety issue: No ]Treatment compliance
- Performance [ Time Frame: 1, 2, 3, 4, and 5 years ] [ Designated as safety issue: No ]Performance-based measures of visual function.
- Progression [ Time Frame: 1, 2, 3, 4. and 5 years ] [ Designated as safety issue: No ]Progression of Disc Damage Likelihood Scale (DDLS)
|Study Start Date:||October 2011|
|Estimated Study Completion Date:||December 2017|
|Estimated Primary Completion Date:||July 2017 (Final data collection date for primary outcome measure)|
You are being asked to participate in this research study because you have glaucoma, which is the second leading cause of blindness in the world and accounts for 15% of blindness worldwide. Vision loss caused by glaucoma can significantly worsen your health-related quality of life. Despite the fact that glaucoma has such a big impact on a large number of people, research examining the long-term effects of glaucoma-related vision loss on one's quality of life is scarce.
The purpose of this study is to look at the long-term effect of this condition on your quality of life so that we may gain valuable information about what factors influence the quality of life of people with glaucoma. To participate in this study, you will need to allow us to perform clinical tests on your eyes, to self-report your well-being and health-related quality of life, and to let us know how well you perform your daily life activities.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01476644
|Contact: Sheryl S Wizov, COAemail@example.com|
|Contact: Jeanne Molineaux, COAfirstname.lastname@example.org|
|United States, Pennsylvania|
|Wills Eye Institute||Recruiting|
|Philadelphia, Pennsylvania, United States, 19107|
|Contact: Sheryl S Wizov, COA 215-928-3221 email@example.com|
|Contact: Jeanne Molineaux, COA 215-825-4713 firstname.lastname@example.org|
|Sub-Investigator: Leslie J Katz, MD|
|Sub-Investigator: Jonathan S Myers, MD|
|Sub-Investigator: Marlene R Moster, MD|
|Sub-Investigator: Courtland M Schmidt, MD|
|Sub-Investigator: Michael S Pro, MD|
|Sub-Investigator: Scott J Fudemberg, MD|
|Sub-Investigator: Anand Mantravadi, MD|
|Principal Investigator:||George L Spaeth, MD||Glaucoma Service, Wills Eye Institute|