Treatment of APAP Toxicity With IV and Oral NAC 2008-2011
Retrospective chart review of patients who receive N-acetylcysteine for Acetaminophen(APAP) toxicity to assess length of oral vs. IV treatment and the effect of a Clinical Pharmacology and Toxicology division in the management of APAP ingestions.
|Study Design:||Observational Model: Case-Only
Time Perspective: Retrospective
|Official Title:||Treatment of Acetaminophen Toxicity With Intravenous vs. Oral N-acetylcysteine: A Retrospective Review|
- Length of NAC treatment in hours [ Time Frame: Retrospective data collection for patient's hospital admission, max estimated 5days ] [ Designated as safety issue: No ]Length of NAC treatment (in hours) for both IV and PO formulations used in patients with APAP toxicity
- Pharmacology & Toxicology consults [ Time Frame: Retrospective data collection for length of patient's hospital admission, max estimated 5 days ] [ Designated as safety issue: No ]Documenting whether or not a pharmacology & toxicology consult was obtained during the patient's hospital admission for APAP toxicity
|Study Start Date:||June 2011|
|Study Completion Date:||November 2011|
|Primary Completion Date:||August 2011 (Final data collection date for primary outcome measure)|
Patients receiving oral NAC treatment after an acute acetaminophen ingestion.
Patients receiving IV NAC after an acute Acetaminophen ingestion.
|United States, Ohio|
|Children's Hospital Medical Center of Akron|
|Akron, Ohio, United States, 44308|
|Principal Investigator:||Martha Blackford, PharmD||CHMCA|