MicroRNA Expression in Human Blood Serum and Vitreous Body
This study is currently recruiting participants.
Verified October 2011 by Kyorin University
Sponsor:
Kyorin University
Information provided by (Responsible Party):
Kazunari Hirota, Kyorin University
ClinicalTrials.gov Identifier:
NCT01462734
First received: October 26, 2011
Last updated: October 27, 2011
Last verified: October 2011
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Purpose
MicroRNAs are important regulators of many cellular functions but their expression profile in human vitreous is still unclear. Aim of this study is to investigate microRNA expression profile by PCR in human vitreous of macula hole patients which is suggested to be similar to that of healthy patients.
| Condition | Intervention |
|---|---|
|
MicroRNA Expression Profile in Human Vitreous |
Procedure: human vitreous and blood serum sampling, PCR |
| Study Type: | Observational |
| Study Design: | Observational Model: Case-Only Time Perspective: Prospective |
| Official Title: | MicroRNA Expression in Human Blood Serum and Vitreous Body |
Further study details as provided by Kyorin University:
Primary Outcome Measures:
- MicroRNA expression profile in human vitreous investigated by PCR [ Time Frame: 1month ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples With DNA
3ml of blood serum and 1ml of vitreous
| Estimated Enrollment: | 10 |
| Study Start Date: | October 2011 |
| Estimated Primary Completion Date: | December 2014 (Final data collection date for primary outcome measure) |
| Groups/Cohorts | Assigned Interventions |
|---|---|
|
human vitreous, human blood serum, PCR
Vitreous and bloodserum samples from macula hole patients without previous ocular or sysytemic disease
|
Procedure: human vitreous and blood serum sampling, PCR
1ml of human vitreous and 3ml of human blood serum
|
Eligibility| Genders Eligible for Study: | Female |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Study Population
Female pateints undergoing vitrectomy for macula hole without previous ocular or systemic disease
Criteria
Inclusion Criteria:
- Female macula hole patients without previous ocular or systemic disease.
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01462734
Contacts
| Contact: Hiroshi Keino, Assistant proffesor | keino@eye-center.org | |
| Contact: Kazunari Hirota, MD | hirota@eye-center.org |
Locations
| Japan | |
| Kyorin University School Of Medicine | Recruiting |
| Tokyo, Mitakasi Sinkawa6-20-2, Japan, 181-8611 | |
| Contact: Hiroshi Keino, Assistant Proffesor keino@eye-center.org | |
| Contact: Kazunari Hirota, MD hirota@eye-center.org | |
Sponsors and Collaborators
Kyorin University
More Information
No publications provided
| Responsible Party: | Kazunari Hirota, MD, Kyorin University |
| ClinicalTrials.gov Identifier: | NCT01462734 History of Changes |
| Other Study ID Numbers: | No. 461 |
| Study First Received: | October 26, 2011 |
| Last Updated: | October 27, 2011 |
| Health Authority: | Japan: Institutional Review Board |
ClinicalTrials.gov processed this record on May 19, 2013