MicroRNA Expression in Human Blood Serum and Vitreous Body

This study is currently recruiting participants. (see Contacts and Locations)
Verified October 2011 by Kyorin University
Sponsor:
Information provided by (Responsible Party):
Kazunari Hirota, Kyorin University
ClinicalTrials.gov Identifier:
NCT01462734
First received: October 26, 2011
Last updated: October 27, 2011
Last verified: October 2011
  Purpose

MicroRNAs are important regulators of many cellular functions but their expression profile in human vitreous is still unclear. Aim of this study is to investigate microRNA expression profile by PCR in human vitreous of macula hole patients which is suggested to be similar to that of healthy patients.


Condition Intervention
MicroRNA Expression Profile in Human Vitreous
Procedure: human vitreous and blood serum sampling, PCR

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: MicroRNA Expression in Human Blood Serum and Vitreous Body

Further study details as provided by Kyorin University:

Primary Outcome Measures:
  • MicroRNA expression profile in human vitreous investigated by PCR [ Time Frame: 1month ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

3ml of blood serum and 1ml of vitreous


Estimated Enrollment: 10
Study Start Date: October 2011
Estimated Primary Completion Date: December 2014 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
human vitreous, human blood serum, PCR
Vitreous and bloodserum samples from macula hole patients without previous ocular or sysytemic disease
Procedure: human vitreous and blood serum sampling, PCR
1ml of human vitreous and 3ml of human blood serum

  Eligibility

Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Female pateints undergoing vitrectomy for macula hole without previous ocular or systemic disease

Criteria

Inclusion Criteria:

  • Female macula hole patients without previous ocular or systemic disease.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01462734

Contacts
Contact: Hiroshi Keino, Assistant proffesor keino@eye-center.org
Contact: Kazunari Hirota, MD hirota@eye-center.org

Locations
Japan
Kyorin University School Of Medicine Recruiting
Tokyo, Mitakasi Sinkawa6-20-2, Japan, 181-8611
Contact: Hiroshi Keino, Assistant Proffesor       keino@eye-center.org   
Contact: Kazunari Hirota, MD       hirota@eye-center.org   
Sponsors and Collaborators
Kyorin University
  More Information

No publications provided

Responsible Party: Kazunari Hirota, MD, Kyorin University
ClinicalTrials.gov Identifier: NCT01462734     History of Changes
Other Study ID Numbers: No. 461
Study First Received: October 26, 2011
Last Updated: October 27, 2011
Health Authority: Japan: Institutional Review Board

ClinicalTrials.gov processed this record on July 22, 2014