Attentional Training for Smoking Cessation Via Handheld Device or Personal Computer

The recruitment status of this study is unknown because the information has not been verified recently.
Verified October 2011 by Boston University.
Recruitment status was  Recruiting
Sponsor:
Collaborator:
Harvard University
Information provided by (Responsible Party):
Samantha Moshier, M.A., Boston University
ClinicalTrials.gov Identifier:
NCT01458834
First received: October 22, 2011
Last updated: NA
Last verified: October 2011
History: No changes posted
  Purpose

Several studies indicate that cigarette smokers show an attentional bias for cigarette-related cues, meaning that they more quickly detect and attend to and have more difficulty disengaging in cigarette-related information than neutral information. This bias is associated with craving and relapse following attempts to quit. This experiment will examine whether a computerized attentional training procedure will successfully reduce attentional bias towards smoking cues and reduce craving in regular cigarette smokers. The attentional training will be administered in a novel format in which participants complete 5-minute long training sessions 3 times per day and can complete the trainings via home computer or handheld device such as the iPhone, Android phone, or iPod touch. A baseline assessment in the laboratory will measure attentional bias to smoking cues and craving following smoking cue exposure. Participants will then be randomly assigned to either the active training condition or a control condition. In both conditions, participants will be asked to complete brief training sessions 3 times daily for one week using their personal computer or handheld device. Following one week of training, participants will return to the lab for endpoint assessment of attentional bias and craving. The investigators hypothesize that compared to the control condition, the active training condition will significantly reduce attentional bias toward smoking related cues and cue-induced cigarette craving.


Condition Intervention
Smoking
Behavioral: Attention bias modification task
Behavioral: Control Condition

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Treatment
Official Title: Attentional Training for Smoking Cessation Via Handheld Device or Personal Computer

Resource links provided by NLM:


Further study details as provided by Boston University:

Primary Outcome Measures:
  • Brief Questionnaire of Smoking Urges (QSU-Brief) [ Time Frame: Assessed at baseline and endpoint visits (one week apart) ] [ Designated as safety issue: No ]
  • Attentional Bias Scores [ Time Frame: Assessed at baseline and endpoint visits (one week apart) ] [ Designated as safety issue: No ]

Estimated Enrollment: 60
Study Start Date: September 2011
Estimated Primary Completion Date: July 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Active attention training condition Behavioral: Attention bias modification task
Participants will complete a computerized probe-discrimination task from their home computer or handheld electronic device 3 times per day for one week. Each training session will consist of 160 trials. In each trial, two pictures (smoking-related or neutral) will appear on the screen simultaneously and then disappear. An arrow will appear in the location of one of the pictures (< or >). Participants are asked to quickly identify the direction of the arrow by pressing a button. In the active training task, the arrow will replace the neutral pictures 80% of the time.
Placebo Comparator: Control condition Behavioral: Control Condition
Participants will complete a computerized probe-discrimination task from their home computer or handheld electronic device 3 times per day for one week. Each training session will consist of 160 trials. In each trial, two pictures (smoking-related or neutral) will appear on the screen simultaneously and then disappear. An arrow will appear in the location of one of the pictures (< or >). Participants are asked to quickly identify the direction of the arrow by pressing a button. In the control training task, the arrow will replace the neutral and smoking-related pictures with equal frequency.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  1. Age 18-65.
  2. Familiarity with a computer keyboard and mouse.
  3. Must own a iPhone, iPod Touch, or Google Android-based phone (such as the Droid or Nexus One) or have regular access to the Internet via personal computer.
  4. Current regular smoker, as defined by self-reported use of at least 1 year and a current average of at least 10 cigarettes smoked per day.

Exclusion Criteria:

1. Individuals with current suicidality (determined by a score of 2 or 3 on item 9 of the Beck Depression Inventory given following consent) will be excluded from further participation.

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01458834

Locations
United States, Massachusetts
Boston University Recruiting
Boston, Massachusetts, United States, 02215
Contact: Samantha Moshier, MA    617-353-9610    smoshier@bu.edu   
Sponsors and Collaborators
Boston University
Harvard University
Investigators
Principal Investigator: Samantha Moshier, MA Boston University
  More Information

No publications provided

Responsible Party: Samantha Moshier, M.A., Principal Investigator, Boston University
ClinicalTrials.gov Identifier: NCT01458834     History of Changes
Other Study ID Numbers: BU-2453
Study First Received: October 22, 2011
Last Updated: October 22, 2011
Health Authority: United States: Institutional Review Board

Keywords provided by Boston University:
Smoking
Attentional bias
Craving

ClinicalTrials.gov processed this record on October 20, 2014