In Vivo Optical Spectroscopy Monitoring in a New Model of Muscular Compartment Syndrome
Recruitment status was Recruiting
Muscular compartment syndrome (MCS) is consecutive to an increase in intramuscular compartment pressures, and is a rare but serious postoperative complication.
The INVOS (In Vivo Optical Spectroscopy) monitors tissular oxygenation continuously and non-invasively.
The objective is to develop a model mimicking the physiopathology of MCS to assess the interest of the INVOS in this case.
|Study Design:||Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Basic Science
|Official Title:||In Vivo Optical Spectroscopy Monitoring in a New Model of Muscular Compartment Syndrome.|
- Comparison between INVOS monitoring and Electromyography [ Time Frame: 45 minutes ] [ Designated as safety issue: Yes ]A comparison will be made between the INVOS monitoring and non invasive (transcutaneous) EMG monitoring (AP Block), to determine the accuracy of the INVOS monitoring to predict AP block.
|Study Start Date:||October 2011|
|Estimated Study Completion Date:||December 2011|
|Estimated Primary Completion Date:||December 2011 (Final data collection date for primary outcome measure)|
Inflation of a tourniquet
Inflation of a tourniquet (pressure equal to the mean arterial pressure) obtaining a model of slight venous congestion and arterial hypoperfusion
After inflation of a tourniquet (pressure equal to the mean arterial pressure, we will obtain a model of slight venous congestion and arterial hypoperfusion. A comparison will be made between INVOS monitoring, sensory deficits, pain, electromyography and invasive pressure.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01452425
|Contact: Patrice Forget, M.D.||+email@example.com|
|Cliniques universitaires Saint-Luc||Recruiting|
|Brussels, Belgium, 1200|
|Contact: Patrice Forget, M.D. +3227641821 firstname.lastname@example.org|
|Principal Investigator: Patrice Forget, M.D.|
|Principal Investigator:||Patrice Forget, M.D.||UCL|