Molecular Mediators of Nerve Injury Signaling

This study is enrolling participants by invitation only.
Sponsor:
Information provided by (Responsible Party):
Rambam Health Care Campus
ClinicalTrials.gov Identifier:
NCT01437332
First received: September 19, 2011
Last updated: NA
Last verified: September 2011
History: No changes posted
  Purpose

Specific proteins and other signaling molecules are increased and decreased following nerve injury. Some of these are important in producing pain or explaining why pain persists after traumatic nerve injuries or in disease states such as diabetes. In this study, the investigators hypothesize that it is possible to detect changes in specific signaling molecules and that these will provide insights into novel treatment strategies. The patients to be included are those who are undergoing the removal of tissue during surgery. The tissues that would otherwise be discarded will be included in the study as appropriate.


Condition
Diabetes
Nerve Injury
Chronic Neuropathic Pain

Study Type: Observational
Study Design: Observational Model: Ecologic or Community
Time Perspective: Prospective
Official Title: Molecular Mediators of Nerve Injury Signaling

Resource links provided by NLM:


Further study details as provided by Rambam Health Care Campus:

Estimated Enrollment: 50
Study Start Date: September 2011
Estimated Primary Completion Date: September 2016 (Final data collection date for primary outcome measure)
Groups/Cohorts
Diabetes
Nerve injury
Other

  Eligibility

Ages Eligible for Study:   18 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Patients undergoing surgical procedures at Rambam Health Care Campus wherein the surgeon and PI determine appropriateness for study

Criteria

Inclusion Criteria:

  • patients undergoing surgery where tissue removal is anticipated

Exclusion Criteria:

  • age younger than 18
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01437332

Locations
Israel
Rambam Health Care Campus
Haifa, Israel, 31096
Sponsors and Collaborators
Rambam Health Care Campus
  More Information

Publications:
Responsible Party: Rambam Health Care Campus
ClinicalTrials.gov Identifier: NCT01437332     History of Changes
Other Study ID Numbers: 0356-11-RMB
Study First Received: September 19, 2011
Last Updated: September 19, 2011
Health Authority: Israel: Israel Medical Association

Additional relevant MeSH terms:
Neuralgia
Wounds and Injuries
Pain
Neurologic Manifestations
Nervous System Diseases
Peripheral Nervous System Diseases
Neuromuscular Diseases
Signs and Symptoms

ClinicalTrials.gov processed this record on July 29, 2014