Mucin Balls and Corneal Inflammation Events

Inclusion Criteria:

• At least 18 years
• Free of any active anterior segment disorders that would preclude safe contact lens wear. Active anterior segment disorders and evidence of central microbial keratitis (via a large, >1mm central deep stromal scar) are not allowed. However, evidence of past CLPU will be allowed so long as no more then three such scars are detected bilaterally. Evidence of more than 3 CLPU-like scars places excessive risk on the subject for a subsequent CIE.
• Correctable vision to 20/25 or better in each eye with spectacles. Amblyopia will be excluded.
• Flat and steep corneal curvatures from keratometry readings must be between 39.00 and 48.50 D, respectively.
• Own or agree to purchase a pair of spectacles that can be worn when lenses are removed or in cases of ocular discomfort or emergency.
• Correctable vision to 20/30 or better at distance with dispensed contact lenses.

Exclusion Criteria:

• Use/wear of rigid gas permeable lenses within the last 30 days or PMMA lenses within the last 3 months.
• Immunocompromising disease or insulin dependent diabetes or any other systemic disease that in the investigator's opinion will affect ocular health or increase risk during extended wear.
• Chronic use of systemic corticosteroids (with the exception of corticosteroid inhalers) or any other medication that in the investigator's opinion will affect ocular physiology or study participation.
• Ocular disease or condition such as aphakia, corneal dystrophies, corneal edema, external ocular infection, iritis, or had any anterior segment surgery.
• Use of any ocular medications in the last 2 weeks.
• Less than or equal to grade 2 on any of the slit lamp observations of: upper tarsal papilla, corneal staining, corneal neovascularization, conjunctival injection, and lid erythema or scales.
• Currently pregnant or lactating.
• Smoker
• Swimming routine of more than twice per month.