Studying Biomarkers in Samples From Patients With Rhabdomyosarcoma
RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
PURPOSE: This research trial studies biomarkers in samples from patients with rhabdomyosarcoma.
Genetic: RNA analysis
Genetic: gene expression analysis
Other: laboratory biomarker analysis
|Official Title:||A Retrospective Study on the Diagnostic Value of Serum miR-206 in Rhabdomyosarcoma|
- Serum miR-206 as a biomaker for RMS [ Designated as safety issue: No ]
|Study Start Date:||September 2011|
|Estimated Primary Completion Date:||December 2011 (Final data collection date for primary outcome measure)|
- Determine whether circulating muscle-specific microRNAs, especially serum miR-206, are potential biomarkers for rhabdomyosarcoma (RMS).
OUTLINE: Archived serum samples are analyzed for miR-206 expression.
PROJECTED ACCRUAL: A total of 15 samples from patients with alveolar rhabdomyosarcoma (RMS), 15 from patients with embryonal RMS, and 10 from patients without RMS will be accrued for this study.
|Principal Investigator:||Hajime Hosoi||Kyoto Prefectural University of Medicine|