Iron Metabolism in Dragon Boat Athletes
This study has been completed.
Sponsor:
University of Giessen
Collaborators:
MVZ für Laboratoriumsmedizin Koblenz
Deutscher Drachenboot Verband e.V.
Information provided by (Responsible Party):
Andree Hillebrecht, University of Giessen
ClinicalTrials.gov Identifier:
NCT01431118
First received: August 31, 2011
Last updated: July 21, 2012
Last verified: July 2012
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Purpose
The purpose of the study is:
- To investigate the effect of sport-specific stress in the iron metabolism of dragon boat athletes
- To investigate the effects of sport-specific stress in the activity of pro-hepcidin and hepcidin
| Condition | Intervention |
|---|---|
|
Anaemia |
Other: specific dragon boating training intervention Other: specific dragon boat intervention |
| Study Type: | Interventional |
| Study Design: | Allocation: Non-Randomized Intervention Model: Single Group Assignment Masking: Single Blind (Investigator) Primary Purpose: Diagnostic |
| Official Title: | Iron Metabolism in Dragon Boat Athletes - An Analysis of Changes in Blood Count Parameters Under Sport-specific Stress |
Resource links provided by NLM:
Further study details as provided by University of Giessen:
Primary Outcome Measures:
- change from Baseline in prohepcidin after performing dragonboating [ Time Frame: pre and post exercise intervention at the same day ] [ Designated as safety issue: No ]one meassurement of prohepcidin immediate before and within three hours after performing two to four specific dragonboat interventions at the same day
Secondary Outcome Measures:
- haematocrit [ Time Frame: pre and post exercise intervention at the same day ] [ Designated as safety issue: No ]one meassurement of haematocrit immediate before and within three hours after performing two to four specific dragonboat intervention at the same day
- value of reticulocytes [ Time Frame: pre exercise ] [ Designated as safety issue: No ]one meassurement of reticulocytes immediate before performing two to four specific dragonboat interventions
- value of hypochromic erythrocytes [ Time Frame: pre exercise ] [ Designated as safety issue: No ]one meassurement of hypochromic erythrocytes immediate before performing two to four specific dragonboat interventions
- change from Baseline in serum iron after performing dragonboating [ Time Frame: pre and post exercise intervention at the same day ] [ Designated as safety issue: No ]one meassurement of serum iron immediate before and within three hours after performing two to four specific dragonboat interventions at the same day
- value of transferrin [ Time Frame: pre exercise ] [ Designated as safety issue: No ]one meassurement of transferrin immediate before performing two to four specific dragonboat interventions
- value of transferrin saturation [ Time Frame: pre exercise ] [ Designated as safety issue: No ]one meassurement of transferrin saturation immediate before performing two to four specific dragonboat interventions
- value of ferritin [ Time Frame: pre exercise ] [ Designated as safety issue: No ]one meassurement of ferritin immediate before performing two to four specific dragonboat interventions
- change from Baseline in hepcidin after performing dragonboating [ Time Frame: pre and post exercise intervention at the same day ] [ Designated as safety issue: No ]one meassurement of hepcidin immediate before and within three hours after performing two to four specific dragonboat interventions at the same day
| Estimated Enrollment: | 40 |
| Study Start Date: | April 2011 |
| Study Completion Date: | April 2012 |
| Primary Completion Date: | April 2012 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
Active Comparator: sports intervention male
male athletes of the german national dragon boat team
|
Other: specific dragon boating training intervention
male athletes of the german national dragon boat team performing three specific training units at one day
|
|
Active Comparator: sports intervention women
women athletes of the german national dragon boat team
|
Other: specific dragon boat intervention
women athletes of the german national dragon boat team performing two specific training units and one weight lifting test at one day
|
Detailed Description:
This investigation evaluates the effects of sport-specific stress in iron metabolism of dragon boat athletes. Recent studies showed a significant increase in hepcidin activity under exercise (Röcker L. et al.(2005): Iron regulatory protein hepcidin is increased in female athletes after a marathon. European Journal of Applied Physiology, S. 95, 569-571)which possibly influences the iron metabolism.
In particular in this investigation the activity of pro-hepcidin and hepcidin under sport-specific stress is analysed. Therefore elite dragonboat athletes will be included to this study. Every athlete is tested once. At one exercise day from every athlete the iron metabolism especially the change of hepcidin, prohepcidin and iron before and after a specific dragonboat intervention is analysed.
Eligibility| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
Criteria
Inclusion Criteria:
- athletes performing dragon boat sport
Exclusion Criteria:
- acute clinically significant intercurrent diseases
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01431118
Sponsors and Collaborators
University of Giessen
MVZ für Laboratoriumsmedizin Koblenz
Deutscher Drachenboot Verband e.V.
Investigators
| Principal Investigator: | Andree Hillebrecht, Dr. med. | Department of sportsmedicine- University Giessen |
More Information
No publications provided
| Responsible Party: | Andree Hillebrecht, Dr.med., University of Giessen |
| ClinicalTrials.gov Identifier: | NCT01431118 History of Changes |
| Other Study ID Numbers: | Gi-02-2011 |
| Study First Received: | August 31, 2011 |
| Last Updated: | July 21, 2012 |
| Health Authority: | Germany: Ethics Commission |
Keywords provided by University of Giessen:
|
iron metabolism hepcidin dragon boating sport-specific stress |
iron anaemia sport |
Additional relevant MeSH terms:
|
Anemia Hematologic Diseases |
ClinicalTrials.gov processed this record on May 16, 2013