Outcomes of 3 Incision-size-dependent Phacoemulsification Systems
The purpose of this study is to compare the outcomes of cataract surgery performed with three incision-sizedependent phacoemulsification systems (1.8, 2.2 and 3.0 mm).
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Clinical Evaluation of Three Incision-size-dependent Phacoemulsification Systems|
- Central cornea endothelial cell loss and surgically induced astigmatism [ Time Frame: 3 months ] [ Designated as safety issue: Yes ]
- best-corrected visual acuity [ Time Frame: 3 months ] [ Designated as safety issue: No ]
|Study Start Date:||July 2010|
|Study Completion Date:||May 2011|
|Primary Completion Date:||May 2011 (Final data collection date for primary outcome measure)|
1.8-mm-incision-size phacoemulsification system
2.2-mm-incision-size phacoemulsification system
3.0-mm-incision-size phacoemulsification system
It is generally the case that smaller corneal cataract surgical incisions are associated with more rapid wound healing, more stable corneal biomechanical properties and less surgically induced astigmatism (SIA). With the development of phacoemulsification and foldable intraocular lenses (IOL) during recent decades, the size of clear corneal incisions has been reduced from 3.2-mm (coaxial small incision) to 1.4-mm (bimanual microincision). Microincision cataract surgery (MICS), including bimanual and microcoaxial phacoemulsification, has attracted much interest recently, due to its safety and ease of learning. However, the superiority of coaxial microincision cataract surgery as compared conventional coaxial cataract surgery is still not certain, because microincision phacoemulsification may result in longer ultrasound time (UST), the use of more ultrasonic power and consequently higher endothelial cell loss (ECL).
In our previous studies of the OZil Torsional phacoemulsification system (Infiniti, Alcon), we reported that the safety and effectiveness of cataract surgery are influenced by many factors, including the blade used to create the incision, the phacoemulsification apparatus, and the IOL and mode of IOL delivery, which together constitute a surgical system, whose outcomes are restricted by the best performance of each component. Today, microcoaxial phacoemulsification is in wide use for cataract surgery, but the lower limits of incision size should be understood in the context of the various components of the surgical system.
In this study, we compared the safety and efficacy of three different incision-size-dependent phacoemulsification systems, 1.8, 2.2 and 3.0 mm, and evaluated the relationship between incision size and SIA.
|Zhongshan Ophthalmic Center, Sun Yat-sen U|
|Guangzhou, Guangdong, China, 510060|
|Study Director:||Yizhi Liu, M.D.,Ph.D.||Sun Yat-sen University|